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ELK Biotechnology
SKU(재고 관리 코드):ES9007
PDE3A Rabbit Polyclonal Antibody
PDE3A Rabbit Polyclonal Antibody
PDE3A Rabbit Polyclonal Antibody
Overview
| Product name: | PDE3A rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 250-330 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 125kD |
| GeneID（Human）: | 5139 |
| Human Swiss-Prot No: | Q14432 |
| Cellular localization: | Membrane ; Multi-pass membrane protein . Cytoplasm, cytosol . |
| Background: | This gene encodes a member of the cGMP-inhibited cyclic nucleotide phosphodiesterase (cGI-PDE) family. cGI-PDE enzymes hydrolyze both cAMP and cGMP, and play critical roles in many cellular processes by regulating the amplitude and duration of intracellular cyclic nucleotide signals. The encoded protein mediates platelet aggregation and also plays important roles in cardiovascular function by regulating vascular smooth muscle contraction and relaxation. Inhibitors of the encoded protein may be effective in treating congestive heart failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011], |
| Species Reactivity: | Human;Mouse;Rat |
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