Phospho-B23 (T199) Polyclonal Antibody

NPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified. Alternative splicing results in multiple transcript variants.

The Phospho-B23 (T199) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated B23 protein at threonine 199 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional quality and reliability.

Phosphorylation of B23 at threonine 199 has been implicated in various cellular processes, including cell cycle regulation, nucleolar organization, and ribosome biogenesis. The Phospho-B23 (T199) Polyclonal Antibody offers researchers a valuable tool to investigate the functional significance of this phosphorylation event.

This antibody exhibits excellent specificity, displaying minimal cross-reactivity with non-phosphorylated B23 protein or other related proteins. It has been extensively validated through various experimental techniques, including Western blotting, immunoprecipitation, and immunofluorescence, ensuring accurate and reproducible results.

The Phospho-B23 (T199) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. It is provided in a convenient size, allowing for multiple experiments without compromising performance.

With its exceptional sensitivity and specificity, the Phospho-B23 (T199) Polyclonal Antibody is an indispensable tool for researchers studying the role of B23 phosphorylation in cellular processes.