Phospho-Bcr (Y360) Polyclonal Antibody

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene (BCR, RhoGEF and GTPase activating protein). The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for BCR.

The Phospho-Bcr (Y360) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of phosphorylated Bcr (Y360) protein. This antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. The Phospho-Bcr (Y360) Polyclonal Antibody is ideal for use in a wide range of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.

This antibody is designed to recognize the phosphorylated form of Bcr (Y360) protein, which is a key regulator of cell growth and differentiation. The phosphorylation of Bcr (Y360) is known to play a critical role in the regulation of various cellular processes, including cell cycle progression, apoptosis, and DNA repair. The Phospho-Bcr (Y360) Polyclonal Antibody is therefore an essential tool for researchers studying these processes.

The Phospho-Bcr (Y360) Polyclonal Antibody is produced using high-quality polyclonal antibodies that have been extensively validated for their specificity and sensitivity. This ensures that the antibody is highly specific and sensitive, and can detect even low levels of phosphorylated Bcr (Y360) protein. The antibody is also highly reproducible, ensuring consistent results across multiple experiments.

In summary, the Phospho-Bcr (Y360) Polyclonal Antibody is a highly specific and sensitive antibody designed for the detection of phosphorylated Bcr (Y360) protein. It is an essential tool for researchers studying the regulation of cell growth and differentiation, and is ideal for use in a wide range of applications, including Western blotting, immunoprecipitation, and immunohistochemistry.