Phospho-BID (S78) Polyclonal Antibody

BID (BH3 interacting domain death agonist) encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.

Introducing the Phospho-BID (S78) Polyclonal Antibody, a cutting-edge scientific tool meticulously designed to facilitate advanced research in the field of molecular biology. This antibody, derived from a polyclonal source, exhibits exceptional specificity and sensitivity, enabling precise detection and analysis of phosphorylated BID at serine 78 residue.

Crafted with utmost precision and utilizing state-of-the-art technology, this Phospho-BID (S78) Polyclonal Antibody offers researchers an invaluable resource to unravel the intricate mechanisms underlying cellular signaling pathways. Its high affinity for phosphorylated BID at serine 78 ensures accurate identification and quantification of this critical post-translational modification, thereby facilitating comprehensive investigations into the functional implications of BID phosphorylation.

The Phospho-BID (S78) Polyclonal Antibody boasts an exceptional performance profile, characterized by its remarkable specificity and minimal cross-reactivity with non-phosphorylated BID or other related proteins. This attribute guarantees reliable and reproducible results, empowering researchers to confidently explore the role of BID phosphorylation in diverse biological processes, including apoptosis, cell survival, and cellular stress responses.

Furthermore, this antibody's versatility extends to various experimental applications, including Western blotting, immunoprecipitation, immunofluorescence, and immunohistochemistry. Its compatibility with multiple techniques ensures flexibility and convenience, enabling researchers to employ their preferred methodology while maintaining the highest standards of accuracy and precision.

In summary, the Phospho-BID (S78) Polyclonal Antibody represents a breakthrough in molecular biology research, offering an indispensable tool for investigating the intricate world of BID phosphorylation. With its exceptional specificity, sensitivity, and compatibility with various experimental techniques, this antibody empowers researchers to delve deeper into the complexities of cellular signaling pathways, ultimately advancing our understanding of fundamental biological processes.