Phospho-C/EBP  Alpha (S21) Polyclonal Antibody

This intronless gene (CEBPA) encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein (CCAAT/enhancer binding protein alpha) functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of CEBPA is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

The Phospho-C/EBP Alpha (S21) Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of phosphorylated C/EBP Alpha protein. This antibody is produced using advanced techniques, ensuring high affinity and specificity towards the phosphorylated form of C/EBP Alpha at serine 21 residue.

C/EBP Alpha is a transcription factor that plays a crucial role in the regulation of various cellular processes, including differentiation, proliferation, and metabolism. Phosphorylation of C/EBP Alpha at serine 21 has been implicated in the modulation of its transcriptional activity and stability, making it an important target for research in the field of molecular biology.

The Phospho-C/EBP Alpha (S21) Polyclonal Antibody exhibits exceptional performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It has been extensively validated for its specificity and sensitivity, ensuring reliable and reproducible results.

This antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size, allowing for multiple experiments without compromising the quality and performance. The Phospho-C/EBP Alpha (S21) Polyclonal Antibody is compatible with a wide range of sample types, including cell lysates, tissue extracts, and purified proteins.

With its exceptional specificity and sensitivity, the Phospho-C/EBP Alpha (S21) Polyclonal Antibody is an indispensable tool for researchers studying the phosphorylation status and functional implications of C/EBP Alpha protein. Its reliable performance and ease of use make it an ideal choice for both basic research and drug discovery applications.