Phospho-C/EBP  Alpha (T230) Polyclonal Antibody

CEBPA encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The CCAAT/enhancer binding protein alpha functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons.

The Phospho-C/EBP Alpha (T230) Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of phosphorylated C/EBP Alpha protein at threonine 230 residue. This antibody is produced using advanced polyclonal antibody technology, ensuring exceptional sensitivity and specificity.

C/EBP Alpha is a transcription factor that plays a crucial role in the regulation of various cellular processes, including cell differentiation, proliferation, and metabolism. Phosphorylation of C/EBP Alpha at threonine 230 has been implicated in the modulation of its transcriptional activity and stability.

The Phospho-C/EBP Alpha (T230) Polyclonal Antibody has been extensively validated for its performance in various applications, including Western blotting, immunoprecipitation, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated C/EBP Alpha protein, ensuring accurate and specific detection of the phosphorylated form.

With its high affinity and specificity, this antibody enables researchers to investigate the role of phosphorylated C/EBP Alpha in cellular processes and disease pathogenesis. It is an invaluable tool for studying signal transduction pathways, protein-protein interactions, and post-translational modifications.

The Phospho-C/EBP Alpha (T230) Polyclonal Antibody is supplied as a ready-to-use solution, eliminating the need for time-consuming antibody preparation. It is provided in a convenient size, ensuring cost-effectiveness and minimizing wastage.

In summary, the Phospho-C/EBP Alpha (T230) Polyclonal Antibody is a reliable and specific tool for the detection and analysis of phosphorylated C/EBP Alpha protein. Its exceptional performance and versatility make it an essential component of any research involving C/EBP Alpha signaling pathways.