Phospho-CD45 (S1007) Polyclonal Antibody

The protein encoded by PTPRC (protein tyrosine phosphatase, receptor type C) is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of PTPRC, which encode distinct isoforms, have been reported.

Introducing the Phospho-CD45 (S1007) Polyclonal Antibody, a cutting-edge immunological tool meticulously designed to facilitate advanced research in the field of cellular signaling pathways. This highly specific antibody is engineered to target the phosphorylated form of CD45, a transmembrane protein crucial for regulating immune cell activation and differentiation.

Crafted with utmost precision, the Phospho-CD45 (S1007) Polyclonal Antibody exhibits exceptional affinity and selectivity towards the phosphorylated epitope of CD45. Its polyclonal nature ensures enhanced sensitivity and versatility, enabling researchers to explore a wide range of applications, including Western blotting, immunoprecipitation, and immunofluorescence.

With its unrivaled specificity, this antibody enables researchers to delve into the intricate mechanisms underlying CD45 phosphorylation, shedding light on its pivotal role in modulating immune responses. By precisely targeting the phosphorylated form of CD45, this antibody empowers scientists to unravel the complexities of cellular signaling cascades, paving the way for groundbreaking discoveries in immunology and beyond.

The Phospho-CD45 (S1007) Polyclonal Antibody is meticulously manufactured using state-of-the-art techniques, ensuring consistent and reliable results. Rigorous quality control measures guarantee batch-to-batch reproducibility, providing researchers with the utmost confidence in their experimental outcomes.

In summary, the Phospho-CD45 (S1007) Polyclonal Antibody represents a paramount tool for elucidating the intricate intricacies of CD45 phosphorylation and its impact on immune cell function. With its exceptional specificity, versatility, and reliability, this antibody is poised to revolutionize the field of cellular signaling research, empowering scientists to unravel the complexities of immune regulation and drive scientific progress.