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SKU(재고 관리 코드):PAB592Po01

Polyclonal Antibody to Caspase 1 (CASP1)

Polyclonal Antibody to Caspase 1 (CASP1)

UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL;
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.

Product No.

PAB592Po01

Organism Species

Sus scrofa; Porcine (Pig).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPB592Po01-Recombinant Caspase 1 (CASP1)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

0.5mg/ml

Organism Species More

Homo sapiens (Human)

Applications

WB,IHC,ICC/IF

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against CASP1. It has been selected for its ability to recognize CASP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunofluorescence: 5-30µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

PLoS One.

Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion Pubmed:24816434

Fertil Steril

Inflammosome in the human endometrium: further step in the evaluation of the “maternal side” PubMed: 26474737

PLoS One

Synthetic PreImplantation Factor (PIF) prevents fetal loss by modulating LPS induced inflammatory response. pubmed:28704412

Journal of Virology

NS1 protein of 2009 pandemic influenza A virus inhibits porcine NLRP3 inflammasome-mediated interleukin-1 beta production by suppressing ASC ubiquitination Pubmed:29386291

Journal of Translational Medicine

Recurrent pregnancy loss is associated to leaky gut: a novel pathogenic model of endometrium inflammation? Pubmed:29665864

Reproductive Sciences

A role for the inflammasome in spontaneous labor at term Pubmed:27852921

Journal of Virology

CHARACTERIZATION OF PORCINE NLRP3 INFLAMMASOME-MEDIATED INTERLEUKIN-1 BETA PRODUCTION IN RESPONSE TO INFLUENZA A VIRUSES Pubmed: 29386291

ACTA Otorhinolaryngologica Italica

NLRP3 inflammasome expression in lipopolysaccharide-induced otitis media Pubmed: 30676848

American Journal of Reproductive Immunology

Effect of alpha lipoic acid and myoinositol on endometrial inflammasome from recurrent pregnancy loss women Pubmed: 31148259

Taiwanese Journal of Obstetrics & Gynecology

Serum Caspase-1 levels in women with polycystic ovary syndrome Pubmed: 32127139

Iranian Journal of Allergy, Asthma and Immunology

Increased Level of Caspase-1 in the Serum of Relapsing-remitting Multiple Sclerosis (RRMS) Patients


ACTIVITY OF APOPTOSIS MARKERS IN HPV-ASSOCIATED CERVICAL PATHOLOGIES

Norwegian Journal of development of the International Science

CLINICAL AND PATHOGENETIC SIGNIFICANCE OF CHANGES IN PURINE METABOLISM DURING LUNG CANCER

LIFE SCIENCES

The NLRP3 inhibitor dapansutrile attenuates folic acid induced nephrotoxicity via inhibiting inflammasome/caspase-1/IL axis and regulating autophagy/proliferation 34560082

Biol Reprod

The alarmin S100A12 causes sterile inflammation of the human chorioamniotic membranes and preterm birth and neonatal mortality in mice 34632484

J Mol Neurosci

TRPV1 Suppressed NLRP3 Through Regulating Autophagy in Microglia After Ischemia-Reperfusion Injury Pubmed:35041191

Viruses

Influenza A Virus Infection Activates NLRP3 Inflammasome through Trans-Golgi Network Dispersion Pubmed:35062292


Catalog No.

Related products for research use of Sus scrofa; Porcine (Pig) Organism species

Applications (RESEARCH USE ONLY!)

RPB592Po01

Recombinant Caspase 1 (CASP1)

Positive Control; Immunogen; SDS-PAGE; WB.

PAB592Po01

Polyclonal Antibody to Caspase 1 (CASP1)

WB,IHC,ICC/IF

LAB592Po71

Biotin-Linked Polyclonal Antibody to Caspase 1 (CASP1)

WB; IHC; ICC.

 

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