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SKU(재고 관리 코드):PAA853Bo01

Polyclonal Antibody to Caspase 8 (CASP8)

Polyclonal Antibody to Caspase 8 (CASP8)

UOM
Concentration
Organism species

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

PAA853Bo01

Organism Species

Bos taurus; Bovine (Cattle).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPA853Bo01-Recombinant Caspase 8 (CASP8)

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

1mg/ml

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against CASP8. It has been selected for its ability to recognize CASP8 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-3µg/mL;
Immunohistochemistry: 5-30µg/mL;
Immunocytochemistry: 5-30µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Molecular Neurobiology

Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson’s Disease: Modulation of Mitochondrial Perturbations Pubmed:25502462

Journal of Ethnopharmacology

Viscum articulatum Burm. f. aqueous extract exerts antiproliferative effect and induces cell cycle arrest and apoptosis in leukemia cells Pubmed:29555410

Clinical And Experimental Pharmacology And Physiology 

Diallyl sulfide alleviates cisplatin‐induced nephrotoxicity in rats via suppressing NF‐κB downstream inflammatory proteins and p53/Puma signalling pathway Pubmed:29266336

Environmental Toxicology

Antihepatocarcinogenic activity of whey protein concentrate and lactoferrin in diethylnitrosamine‐treated male albino mice Pubmed: 31087429

Environ Toxicol Pharmacol.

Targetingp53/TRAIL/caspase-8 signaling by adiponectin reverses thioacetamide-induced hepatocellular carcinoma in rats Pubmed: 31421311

Journal of Biochemical and Molecular Toxicology

Tranilast attenuates methotrexate‐induced renal and hepatic toxicities: Role of apoptosis‐induced tissue proliferation Pubmed: 32045101

life sciences

Nifuroxazide attenuates experimentally-induced hepatic encephalopathy and the associated hyperammonemia and cJNk/caspase-8/TRAIL activation in rats Pubmed: 32259601

Odontology

Effects of different pulp-capping materials on cell death signaling pathways of lipoteichoic acid-stimulated human dental pulp stem cells Pubmed: 33206337

Int Immunopharmacol

Cardio-protective impact of gabapentin against doxorubicin-induced myocardial toxicity in rats; emphasis on modulation of inflammatory-apoptotic signaling Pubmed: 33199237

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Chemo-preventive effect of crocin against experimentally-induced hepatocarcinogenesis via regulation of apoptotic and Nrf2 signaling pathways Pubmed: 32942000

Environ Sci Pollut Res Int

Potentiation of the apoptotic signaling pathway in both the striatum and hippocampus and neurobehavioral impairment in rats exposed chronically to a low− dose of … Pubmed: 32915453

J Biochem Mol Toxicol

Tranilast abrogates cisplatin©\induced testicular and epididymal injuries: An insight into its modulatory impact on apoptosis/proliferation 34047436


Catalog No.

Related products for research use of Bos taurus; Bovine (Cattle) Organism species

Applications (RESEARCH USE ONLY!)

RPA853Bo01

Recombinant Caspase 8 (CASP8)

Positive Control; Immunogen; SDS-PAGE; WB.

PAA853Bo01

Polyclonal Antibody to Caspase 8 (CASP8)

WB; IHC; ICC; IP.

LAA853Bo81

FITC-Linked Polyclonal Antibody to Caspase 8 (CASP8)

WB; IHC; ICC; IF.

LAA853Bo71

Biotin-Linked Polyclonal Antibody to Caspase 8 (CASP8)

WB; IHC; ICC.

MAA853Bo21

Monoclonal Antibody to Caspase 8 (CASP8)

WB; IHC; ICC; IP.

 

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