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SKU(재고 관리 코드):PAG515Ra01

Polyclonal Antibody to Chymase 1, Mast Cell (CMA1)

Polyclonal Antibody to Chymase 1, Mast Cell (CMA1)

UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL;1:450-1800
;Immunohistochemistry: 5-20µg/mL;1:45-180
;Immunocytochemistry: 5-20µg/mL;1:45-180
;Optimal working dilutions must be determined by end user.

Product No.

PAG515Ra01

Organism Species

Rattus norvegicus (Rat) 

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPG515Ra01-Recombinant Chymase 1, Mast Cell (CMA1)

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

0.91mg/ml

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against CMA1. It has been selected for its ability to recognize CMA1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;1:450-1800
Immunohistochemistry: 5-20µg/mL;1:45-180
Immunocytochemistry: 5-20µg/mL;1:45-180
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Pathobiology

Anti-Angiotensin and Hypoglycemic Treatments Suppress Liver Metastasis of Colon Cancer Cells Karger: 000330169

Clinical and Experimental Metastasis

Diabetes-associated angiotensin activation enhances liver metastasis of colon cancer PubMed: 22552372

Mediators of Inflammation

Mediators of Mast Cells in Bullous Pemphigoid and Dermatitis Herpetiformis Pubmed:25400334

Neurogastroenterology & Motility

Peritoneal mast cell degranulation and gastrointestinal recovery in patients undergoing colorectal surgery Pubmed:25677271

IJC Metab Endocr

The autocrine role of tryptase in pressure overload-induced mast cell activation, chymase release and cardiac fibrosis PubMed: 26722642

Journal of Neuroinflammation

Oral sensitization to whey proteins induces age-and sex-dependent behavioral abnormality and neuroinflammatory responses in a mouse model of food … Pubmed:29685134

Revista do Instituto de Medicina Tropical de São Paulo

Vasoactive intestinal peptide degradation might influence Interleukin-17 expression in cardiac chagasic patients Pubmed: 30365640

Science Advances

Platelets trigger perivascular mast cell degranulation to cause inflammatory responses and tissue injury Pubmed: 32206714

Immunity Inflammation and Disease

Disruption in the balance between apolipoprotein A‐I and mast cell chymase in chronic hypersensitivity pneumonitis Pubmed: 33016012

Microbiol Spectr

Mast Cell-Derived Proteases Induce Endothelial Permeability and Vascular Damage in Severe Fever with Thrombocytopenia Syndrome Pubmed:35612327


Catalog No.

Related products for research use of Rattus norvegicus (Rat) Organism species

Applications (RESEARCH USE ONLY!)

RPG515Ra01

Recombinant Chymase 1, Mast Cell (CMA1)

Positive Control; Immunogen; SDS-PAGE; WB.

PAG515Ra01

Polyclonal Antibody to Chymase 1, Mast Cell (CMA1)

WB; IHC; ICC; IP.

MAG515Ra21

Monoclonal Antibody to Chymase 1, Mast Cell (CMA1)

WB; IHC; ICC; IP.

SEG515Ra

ELISA Kit for Chymase 1, Mast Cell (CMA1)

Enzyme-linked immunosorbent assay for Antigen Detection.

LMG515Ra

Magnetic Luminex Assay Kit for Chymase 1, Mast Cell (CMA1) ,etc.

Magnetic Luminex Assay for Antigen Detection.

 

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