Cloud-clone
SKU(재고 관리 코드):PAA979Po01
Polyclonal Antibody to Cyclophilin A (CYPA)
Polyclonal Antibody to Cyclophilin A (CYPA)
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
Product No.
PAA979Po01
Organism Species
Sus scrofa; Porcine (Pig).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPA979Po01-Recombinant Cyclophilin A (CYPA)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
500µg/mL
Organism Species More
Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against CYPA. It has been selected for its ability to recognize CYPA in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Atherosclerosis |
EMMPRIN and its ligand cyclophilin A regulate MT1-MMP, MMP-9 and M-CSF during foam cell formation PubMed: 19758589 |
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Biomarkers |
Cyclophilin-A: a novel biomarker for untreated male essential hypertension Pubmed: 24164594 |
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Cardiovascular Diabetology |
Plasma level of cyclophilin A is increased in patients with type 2 diabetes mellitus and suggests presence of vascular disease Pubmed:24502618 |
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International Journal of Biological Sciences |
Decrease in Plasma Cyclophilin A Concentration at 1 Month after Myocardial Infarction Predicts Better Left Ventricular Performance and Synchronicity at 6 Months: A Pilot Study in Patients with ST Elevation Myocardial Infarction Pubmed:25552928 |
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Medicine |
Cyclophilin A in Ruptured Intracranial Aneurysm PubMed: 26426668 |
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Mol Cell Biochem |
PPIA rs6850: A> G single-nucleotide polymorphism is associated with raised plasma cyclophilin A levels in patients with coronary artery disease PubMed: 26702934 |
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Medicine (Baltimore) |
Urinary Cyclophilin A as a New Marker for Diabetic Nephropathy: A Cross-Sectional Analysis of Diabetes Mellitus PubMed: 26496315 |
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International Journal of Cardiology |
Cyclophilin A modulates bone marrow-derived CD117(+) cells and enhances ischemia-induced angiogenesisvia the SDF-1/CXCR4 axis. Pubmed:27057951 |
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Clinica Chimica Acta |
Novel findings of secreted cyclophilin A in diabetic nephropathy and its association with renal protection of dipeptidyl peptidase 4 inhibitor pubmed:27823952 |
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Cardiovascular Diabetology |
Cyclophilin A enhances macrophage differentiation and lipid uptake in high glucose conditions: a cellular mechanism for accelerated macro vascular disease in diabetes mellitus. pubmed:27809851 |
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Clinical Science |
Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity Pubmed:29382697 |
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Journal of Molecular Histology |
Cyclophilin a increases CD68 cell infiltration in rat experimental periodontitis Pubmed:29318411 |
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Free Radical Research |
Cyclophilin A and CD147 associate with progression of diabetic nephropathy Pubmed: 30572748 |
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The Kaohsiung Journal of Medical Sciences |
Association of cyclophilin A level and pulse pressure in predicting recurrence of cerebral infarction Pubmed: 31670477 |
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Cells. |
Cyclophilin A/EMMPRIN Axis Is Involved in Pro-Fibrotic Processes Associated with Thoracic Aortic Aneurysm of Marfan Syndrome Patients Pubmed: 31936351 |
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JAMA Neurology |
APPENDIX A: Relationship between cyclophilin A levels and matrix metalloproteinase-9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers … Pubmed: 24030206 |
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Menoufia Medical Journal |
Urinary podocalyxin and cyclophilin A: markers for early detection of type 2 diabetic nephropathy |
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Toxins |
Evaluation of the Therapeutic Effects of Protocatechuic Aldehyde in Diabetic Nephropathy 34437430 |
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Cell Death & Disease |
Proteomic analysis reveals USP7 as a novel regulator of palmitic acid-induced hepatocellular carcinoma cell death Pubmed:35732625 |
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Catalog No. |
Related products for research use of Sus scrofa; Porcine (Pig) Organism species |
Applications (RESEARCH USE ONLY!) |
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RPA979Po01 |
Positive Control; Immunogen; SDS-PAGE; WB. |
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PAA979Po01 |
WB; IHC; ICC; IP. |
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LAA979Po71 |
WB; IHC; ICC. |
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