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SKU(재고 관리 코드):PAC580Hu01

Polyclonal Antibody to Lysyl Oxidase (LOX)

Polyclonal Antibody to Lysyl Oxidase (LOX)

UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL;
;Immunohistochemistry: 5-20µg/mL;
;Immunocytochemistry: 5-20µg/mL;
;Optimal working dilutions must be determined by end user.

Product No.

PAC580Hu01

Organism Species

Homo sapiens (Human).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPC580Hu01-Recombinant Lysyl Oxidase (LOX)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

Rattus norvegicus (Rat), Sus scrofa; Porcine (Pig)

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against LOX. It has been selected for its ability to recognize LOX in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

American Journal of Hematology

The expression of lysyl-oxidase gene family members in myeloproliferative neoplasms. PubMed: 23494965

Current Eye Research

High Glucose Induced Differential Expression of Lysyl Oxidase and Its Isoform in ARPE-19 Cells Pubmed: 22966818

European Journal of Surgical Oncology

Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed: 24246612

Vaccine

Copia autorizada por CDR Ingentaconnect: Source

Arthritis & Rheumatology

Lysyl oxidase is a potential biomarker of fibrosis in systemic sclerosis Pubmed: 24574233

Eur J Surg Oncol.?

Evaluation of serum lysyl oxidase as a blood test for colorectal cancer Pubmed:Pmc4237001

BMC Cancer.

Ionizing radiation induces tumor cell lysyl oxidase secretion Pubmed:Pmc4223762

DNA Cell Biol.

Lysyl Oxidase Genetic Variants Affect Gene Expression in Cervical Cancer Pubmed:24945327

scandinavian journal of immunology

Increased Serum Levels of the IL-33 Neutralizing sST2 in Limited Cutaneous Systemic Sclerosis PubMed: 26095613

Curr Eye Res

Correlation of Aqueous Humor Lysyl Oxidase Activity with TGF-ß Levels and LOXL1 Genotype in Pseudoexfoliation Pubmed:27116380

journal of bone and mineral metabolism

LOX Fails to Substitute for RANKL in Osteoclastogenesis. pubmed:27606829

38

Blocking Surgically Induced Lysyl Oxidase Activity Reduces the Risk of Lung Metastases. pubmed:28445728

Molecular Medicine Reports

Lysyl oxidase is involved in synovial hyperplasia and angiogenesis in rats with collagen‑induced arthritis pubmed:28901438

Revista Española de Cardiología (English Edition)

A Global Assessment of Circulating Prolysyl Oxidase in Nonischemic Patients With Garden-variety Heart Failure With Preserved Ejection Fraction Pubmed:29807761

Molecular Medicine Reports

Lysyl oxidase inhibition via β-aminoproprionitrile hampers human umbilical vein endothelial cell angiogenesis and migration in vitro Pubmed:29393489

Thyroid

Lysyl Oxidase is a key player in BRAF/MAPK pathway-driven thyroid cancer aggressiveness Pubmed: 30398411

Am J Physiol Lung Cell Mol Physiol

Lysyl Oxidase Directly Contributes to Extracellular Matrix Production and Fibrosis in Systemic Sclerosis. Pubmed: 33026236

J Am Heart Assoc

Collagen Cross©\Linking Is Associated With Cardiac Remodeling in Hypertrophic Obstructive Cardiomyopathy 33356379


Catalog No.

Related products for research use of Homo sapiens (Human) Organism species

Applications (RESEARCH USE ONLY!)

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PAC580Hu02

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WB; IHC; ICC; IP.

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WB; IHC; ICC; IP.

LAC580Hu81

FITC-Linked Polyclonal Antibody to Lysyl Oxidase (LOX)

WB; IHC; ICC; IF.

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WB; IHC; ICC.

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WB; IHC; ICC; IP.

SEC580Hu

ELISA Kit for Lysyl Oxidase (LOX)

Enzyme-linked immunosorbent assay for Antigen Detection.

WEC580Hu

Wide-range ELISA Kit for Lysyl Oxidase (LOX)

Enzyme-linked immunosorbent assay for Antigen Detection.

LMC580Hu

Magnetic Luminex Assay Kit for Lysyl Oxidase (LOX) ,etc.

Magnetic Luminex Assay for Antigen Detection.

KSC580Hu01

ELISA Kit DIY Materials for Lysyl Oxidase (LOX)

Main materials for "Do It(ELISA Kit) Yourself"

 

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