제품 정보로 건너뛰기
1 1

Cloud-clone

SKU(재고 관리 코드):PAA087Gu01

Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)

Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1)

UOM
Concentration
Organism species

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

PAA087Gu01

Organism Species

Cavia (Guinea pig ).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPA087Gu01-Recombinant Monocyte Chemotactic Protein 1 (MCP1)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against MCP1. It has been selected for its ability to recognize MCP1 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine Citations
Cytokine Astragaloside IV ameliorates renal injury in streptozotocin-induced diabetic rats through inhibiting NF-κB-mediated inflammatory genes expression. Pubmed: 23434274
Rheumatology International Serum levels of selected chemokines in systemic lupus erythematosus patients Pubmed: 22461186
Food & Function Effects of Hyriopsis cumingii polysaccharides on angiogenesis, macrophage chemotaxis, proliferation and phagocytosis Pubmed:25620195
36 MRTF-A steers an epigenetic complex to activate endothelin-induced pro-inflammatory transcription in vascular smooth muscle cells Pubmed:Pmc4176337
Journal of Trace Elements in Medicine and Biology Adipose tissue chromium and vanadium disbalance in high-fat fed Wistar rats Pubmed:25194956
天津中医药大学学报 巨噬细胞及其相关因子在家兔不稳定斑块中的作用及其机制 Paper:Source
Int J Clin Exp Pathol Rosiglitazone attenuates renal injury caused by hyperlipidemic pancreatitis PubMed: 26191125
Mediators of Inflammation Effects of Intravenous Injection of PubMed: 26063970
Diabetes Protein Inhibitor of Activated STAT 1 (PIAS1) Protects Against Obesity-Induced Insulin Resistance by Inhibiting Inflammation Cascade in Adipose Tissue PubMed: 26324179
Journal of Histochmistry and Cytochmistry Epigallocatechin-3-Gallate Attenuates Unilateral Ureteral Obstruction-Induced Renal Interstitial Fibrosis in Mice PubMed: 25549657
Cell Physiol Biochem MicroRNA-155 Promotes Atherosclerosis Inflammation via Targeting SOCS1 PubMed: 26159489
Exp Biol Med (Maywood) Renoprotective effects of angiotensin receptor blocker and stem cells in acute kidney injury: Involvement of inflammatory and apoptotic markers PubMed: 25825359
Parasitol Res Trypanosoma cruzi infection and benznidazole therapy independently stimulate oxidative status and structural pathological remodeling of the liver tissue in mice PubMed: 25912691
Invest Ophthalmol Vis Sci Simultaneous Increase in Multiple Proinflammatory Cytokines in the Aqueous Humor in Neovascular Glaucoma With and Without Intravitreal Bevacizumab Injection PubMed: 26030108
PLoS One Postoperative changes in aqueous monocyte chemotactic protein-1 levels and bleb morphology after trabeculectomy vs. Ex-PRESS shunt surgery PubMed: 26427058
Veterinary Parasitology Expression of adhesion molecules, chemokines and matrix metallo- proteinases (MMPs) in viable and degenerating stage of Taenia solium metacestode in swine neurocysticercosis PubMed: 26412140
J Pharm Pharmacol Modulation of oxidative and inflammatory cardiac response by nonselective 1‐and 3‐cyclooxygenase inhibitor and benznidazole in mice PubMed: 26105112
Микроэлементы в медицине НАРУШЕНИЕ БАЛАНСА ХРОМА И ВАНАДИЯ В ЖИРОВОЙ ТКАНИ КАК ВОЗМОЖНЫЙ МЕХАНИЗМ ОЖИРЕНИЕ-АССОЦИИРОВАННОЙ ИНСУЛИНОРЕЗИСТЕНТНОСТИ Microelements_Of_Midicine: 2015_2
Front Pharmacol The G-Protein-Coupled Bile Acid Receptor Gpbar1 (TGR5) Inhibits Gastric Inflammation Through Antagonizing NF-κB Signaling Pathway PubMed: 26696888
PLoS One Effects of PB-EPCs on Homing Ability of Rabbit BMSCs via Endogenous SDF-1 and MCP-1. PubMed: 26660527
Scientific Reports The Transcriptional Foundations of Sp110-mediated Macrophage (RAW264. 7) Resistance to Mycobacterium tuberculosis H37Ra Pubmed:26912204
Neural Plasticity Fractalkine Attenuates Microglial Cell Activation Induced by Prenatal Stress Pubmed:27239349
Technologia Alimentaria Decreased adipose tissue zinc content is associated with metabolic parameters in high fat fed Wistar rats abstract:10
International Immunopharmacology Consistency and pathophysiological characterization of a rat polymicrobial sepsis model via the improved cecal ligation and puncture surgery Pubmed:26802602
J Neurochem. Anti‐inflammatory properties of tianeptine on lipopolysaccharide‐induced changes in microglial cells involve toll‐like receptor‐related pathways Pubmed:26640965
Oxidative Medicine and Cellular Longevity Hyperglycemia Aggravates Hepatic Ischemia Reperfusion Injury by Inducing Chronic Oxidative Stress and Inflammation. pubmed:27656261
Comparative Clinical Pathology Identification of some plasma biomarkers associated with early weaning stress in crossbred piglets article:10.1007
clinical chemistry and laboratory medicine The serum concentrations of leptin and MCP-1 independently predict low back pain duration. pubmed:28076310
Journal of Molecular Cell Biology oxLDL antibody inhibits MCP‐1 release in monocytes/macrophages by regulating Ca2+/K+ channel flow pubmed:27995732
Parasitology. Nonsteroidal anti-inflammatory is more effective than anti-oxidant therapy in counteracting oxidative/nitrosative stress and heart disease in T. cruzi-infected mice. pubmed:28134069
Experimental Parasitology Adhesion molecules, chemokines and matrix metallo-proteinases response after albendazole and albendazole plus steroid therapy in swine neurocysticercosis pubmed:28821422
National Natural Scientific Role of Gut-Derived Endotoxin on Type I Collagen Production in the Rat Pancreas after Chronic Alcohol Exposure pubmed:29121396
Evidence-Based Complementary and Alternative Medicine BuShenKangShuai tablet reduces atherosclerotic lesion by improving blood lipids metabolism and inhibiting inflammatory response via TLR4 and NF-κB signaling pathway journals:1758383
International Journal of Clinical and Experimental Pathology Protective effect of high mobility group box-1 silence on diabetic retinopathy: an in vivo study ISSN:1936-2625/IJCEP0055881
Nature Medicine An ALOX12-12-HETE-GPR31 signaling axis is a key mediator of hepatic ischemia-reperfusion injury. pubmed:29227475
Redox Biology STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO2 gradient. pubmed:29078168
Nature Medicine The deubiquitinating enzyme cylindromatosis mitigates nonalcoholic steatohepatitis Pubmed:29291351
NPG Asia Materials Molybdenum disulfide/graphene oxide nanocomposites show favorable lung targeting and enhanced drug loading/tumor-killing efficacy with improved … Articles:am2017225
Clinical Science Metformin attenuates effects of cyclophilin A on macrophages, reduces lipid uptake and secretion of cytokines by repressing decreased AMPK activity Pubmed:29382697
Life Sciences Lipoxin A4 may attenuate the progression of obesity-related glomerulopathy by inhibiting NF-κB and ERK/p38 MAPK-dependent inflammation Pubmed:29499280
Evidence-based Complementary and Alternative Medicine Bushenkangshuai Tablet Reduces Atherosclerotic Lesion by Improving Blood Lipids Metabolism and Inhibiting Inflammatory Response via TLR4 and NF-κB Signaling … Pubmed:29619063
Lasers in Medical Science Evaluation of the therapeutic effect of micro-plasma radio frequency on hypertrophic scars in rabbit ears Pubmed:30003425
Journal of Ocular Pharmacology and Therapeutics Effect of 0.05% Difluprednate Ophthalmic Emulsion on Proinflammatory Cytokine Levels After Retinal Laser Photocoagulation in Rabbits Pubmed:29812993
Journal of Interferon & Cytokine Research Increased Serum MCP-1 Levels in Systemic Vasculitis Patients with Renal Involvement Pubmed: 30230985
Prostaglandins & Other Lipid Mediators Detoxification and activating blood circulation decoction reduces restenosis involving the TLR4/NF-κB pathway after balloon injury Pubmed: 30453089
Molecular Neurobiology Role of Chronic Administration of Antidepressant Drugs in the Prenatal Stress-Evoked Inflammatory Response in the Brain of Adult Offspring Rats … Pubmed: 30610610
Journal Of Clinical Investigation Long non-coding RNA mitigates atherosclerosis by regulating the actin-binding protein NEXN Pubmed: 30589415
Kidney International Wnt/β-catenin signaling mediates both heart and kidney injury in type 2 cardiorenal syndrome Pubmed: 30770217
Biosensors and Bioelectronics A sensitive sandwich-type immunosensor for the detection of MCP-1 based on a rGO-TEPA-Thi-Au nanocomposite and novel RuPdPt trimetallic nanoalloy particles
European Journal of Pharmacology The cordycepin derivative IMM-H007 improves endothelial dysfunction by suppressing vascular inflammation and promoting AMPK-dependent eNOS activation in … Pubmed: 30826323
Experimental and Therapeutic Medicine Effect of stress hyperglycaemia on monocyte chemoattractant protein‑1 levels and the short‑term prognosis of patients with acute ST‑segment elevation myocardial …
Hepatology Integrated Omics Reveals Tollip as an Aggravator and Therapeutic Target for Hepatic Ischemia‐Reperfusion Injury in Mice Pubmed: 31077413
FASEB Journal Rescuing cones and daylight vision in retinitis pigmentosa mice Pubmed: 31199887
Metallomics Lanthanum chloride induces neuron damage by activating the nuclear factor-kappa B signaling pathway in activated microglia Pubmed: 31187842
Hepatology Hepatocyte TRAF 6 Aggravates Hepatic Inflammation and Fibrosis by Promoting Lys6‐Linked Polyubiquitination of ASK 1
journal of cellular and molecular medicine LncRNA HOXA11‐AS regulates calcium oxalate crystal–induced renal inflammation via miR‐124‐3p/MCP‐1 Pubmed: 31680444
Diabetes Histone H3 serine 10 phosphorylation facilitates endothelial activation in diabetic kidney disease Pubmed: 30213824
Biomedicine & Pharmacotherapy Inhibition of CXCL1-CXCR2 axis ameliorates cisplatin-induced acute kidney injury by mediating inflammatory response Pubmed: 31812015
ACTA PHARMACOLOGICA SINICA α-Galactosylceramide and its analog OCH differentially affect the pathogenesis of ISO-induced cardiac injury in mice Pubmed: 32973325
EBioMedicine Modulating endothelial adhesion and migration impacts stem cell therapies efficacy Pubmed: 32942121
PHARMACOLOGICAL RESEARCH Sea cucumbers-derived sterol sulfate alleviates insulin resistance and inflammation in high-fat-high-fructose diet-induced obese mice Pubmed: 32911073
BRITISH JOURNAL OF PHARMACOLOGY A novel apoA‐I mimetic peptide suppresses atherosclerosis by promoting physiological HDL function in apoE−/− mice Pubmed: 32726461
Int Immunopharmacol BNIP3 deletion ameliorated enterovirus 71 infection-induced hand, foot and mouth disease via inhibiting apoptosis, autophagy, and inflammation in mice Pubmed: 32717566
Life Sci Impact of diminazene aceturate on renin-angiotensin system, infectious myocarditis and skeletal myositis in mice: An in vitro and in vivo study Pubmed: 32652140
Life Sciences Curcumin and LOXblock-1 ameliorate ischemia-reperfusion induced inflammation and acute kidney injury by suppressing the semaphorin-plexin pathway. Pubmed: 32603817
Molecular Medicine Reports Aquaporin‑4 deletion ameliorates enterovirus 71 infection in mice Pubmed: 32582978
Life Sci Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway Pubmed: 32428599
JOURNAL OF IMMUNOLOGY RESEARCH β-Defensin Strengthens Antimicrobial Peritoneal Mast Cell Response Pubmed: 32411798
cell metabolism Low-Dose Sorafenib Acts as a Mitochondrial Uncoupler and Ameliorates Nonalcoholic Steatohepatitis Pubmed: 32375062
Nanoscale Research Letters Protective Effects of Carbon Dots Derived from Phellodendri Chinensis Cortex Carbonisata against Deinagkistrodon acutus Venom-Induced Acute Kidney …
J Immunoassay Immunochem Effects of regular exercise on inflammatory biomarkers and lipid parameters in soccer players 33750257
FASEB Bioadv Cyclophilin A induces macrophage apoptosis and enhances atherosclerotic lesions in high©\fat diet©\fed hyperglycemic rabbits 33977232
Hepatology TNIP3 is a novel activator of Hippo©\YAP signaling protecting against hepatic ischemia/reperfusion injury 34133792
Bioactive Materials Construction of heparin-based hydrogel incorporated with Cu5. 4O ultrasmall nanozymes for wound healing and inflammation inhibition 33778192
researchsquare p62 promotes HIV-1 gp120 V3 loop-mediated microglial inflammation by promoting noncanonical activation of Nrf2
Transl Vis Sci Technol Intraocular Pressure-Lowering Effects of Trabeculectomy Versus MicroShunt Insertion in Rabbit Eyes 34357381
Cell Metabolism Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species 34536344
Stroke CCL2 (CC Motif Chemokine Ligand 2) Biomarker Responses in Central Versus Peripheral Compartments After Focal Cerebral Ischemia 34587791
J Ethnopharmacol Identification of potential regulating effect of baicalin on NFκB/CCL2/CCR2 signaling pathway in rats with cerebral ischemia by antibody-based array and … 34699947
Biomed Pharmacother Huangbai liniment and berberine promoted wound healing in high-fat diet/Streptozotocin-induced diabetic rats Pubmed:35430394
Expert Opinion on Therapeutic Targets Dapagliflozin mitigates ovalbumin-prompted airway inflammatory-oxidative successions and associated bronchospasm in a rat model of allergic asthma Pubmed:35549595
Catalog No. Related products for research use of Cavia (Guinea pig ) Organism species Applications (RESEARCH USE ONLY!)
RPA087Gu01 Recombinant Monocyte Chemotactic Protein 1 (MCP1) Positive Control; Immunogen; SDS-PAGE; WB.
PAA087Gu01 Polyclonal Antibody to Monocyte Chemotactic Protein 1 (MCP1) WB; IHC; ICC; IP.
SEA087Gu ELISA Kit for Monocyte Chemotactic Protein 1 (MCP1) Enzyme-linked immunosorbent assay for Antigen Detection.
LMA087Gu Magnetic Luminex Assay Kit for Monocyte Chemotactic Protein 1 (MCP1) ,etc. Magnetic Luminex Assay for Antigen Detection.
KSA087Gu01 ELISA Kit DIY Materials for Monocyte Chemotactic Protein 1 (MCP1) Main materials for "Do It (ELISA Kit) Yourself".
전체 세부 정보 보기