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SKU(재고 관리 코드):PAA837Mu02

Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

Product No.

PAA837Mu02

Organism Species

Mus musculus (Mouse).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPA837Mu02-Recombinant Nitric Oxide Synthase 2, Inducible (NOS2)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

Rattus norvegicus (Rat)

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against NOS2. It has been selected for its ability to recognize NOS2 in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL
Immunohistochemistry: 5-20µg/mL
Immunocytochemistry: 5-20µg/mL
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

High-molecular weight hyaluronan reduced renal PKC activation in genetically diabetic mice PubMed: 20713153

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Hyaluronan reduces inflammation in experimental arthritis by modulating TLR-2 and TLR-4 cartilage expression ScienceDirect: S0925443911001323

FEBS Journal

Adenosine A2a Receptor Activation and Hyaluronan Fragment Inhibition Reduce Inflammation in Mouse Articular Chondrocytes Stimulated with Il-1beta Wiley: source

Gene

Hyaluronan in part mediates IL-1beta-induced inflammation in mouse chondrocytes by up-regulating CD44 receptors ScienceDirect: S0378111911007347

PLoS One

A Novel Mechanism of Formaldehyde Neurotoxicity: Inhibition of Hydrogen Sulfide Generation by Promoting Overproduction of Nitric Oxide PubMed: 23359814

PLoS ONE

Regulation of Microglia Activity by Glaucocalyxin-A: Attenuation of Lipopolysaccharide-Stimulated Neuroinflammation through NF-κB and p38 MAPK Signaling Pathways PlosOne: Source

Journal of Cellular Biochemistry

The inhibition of hyaluronan degradation reduced pro-inflammatory cytokines in mouse synovial fibroblasts subjected to collagen-induced arthritis. PubMed: 22234777

International Immunopharmacology

Amentoflavone inhibits iNOS, COX-2 expression and modulates cytokine profile, NF-κB signal transduction pathways in rats with ulcerative colitis Pubmed: 24126114

Integrative Cancer Therapies

Decalepis hamiltonii inhibits tumor progression and metastasis by regulating the inflammatory mediators and nuclear factor κB subunits Pubmed: 24013642

Food and Chemical Toxicology

Inhibition of UVB-induced skin phototoxicity by a grape seed extract as modulator of nitrosative stress, ERK/NF-kB signaling pathway and apoptosis, in SKH-1 mice Pubmed: 23567245

Experimental Gerontology

Age-related changes in ADMA–DDAH–NO pathway in rat liver subjected to partial ischemia followed by global reperfusion ScienceDirect: S0531556513003331

International Immunopharmacology

Protective effect of marine mangrove Rhizophora apiculata on acetic acid induced experimental colitis by regulating anti-oxidant enzymes, inflammatory mediators and nuclear factor-kappa B subunits ScienceDirect: S1567576913004153

INTERNATIONAL JOURNAL OF MEDICINE AND MEDICAL RESEARCH

L-ARGININE, BUT NOT L-NAME PROTECTS AGAINST LIVER INJURY INDUCED BY EXPERIMENTAL ISCHEMIA-REPERFUSION Tdmu:Source

Molecular Vision

Effects of topically applied tocotrienol on cataractogenesis and lens redox status in galactosemic rats Pubmed:24940038

Journal of Environmental Pathology, Toxicology and Oncology

Protective Effect of?Acacia ferruginea?against Ulcerative Colitis via Modulating Inflammatory Mediators, Cytokine Profile and NF-κB Signal Transduction Pathways Pubmed:24941292

Eur J Cancer Prev.

Utility of Apc-mutant rats with a colitis-associated colon carcinogenesis model for chemoprevention studies Pubmed:25222193

Cell and Tissue Research

Beta-arrestin 1 is involved in the catabolic response stimulated by hyaluronan degradation in mouse chondrocytes Pubmed:25673209

Ann N Y Acad Sci.?

Modulating effect of Biophytum sensitivum extract on rats with acetic acid-induced ulcerative colitis Pubmed:5243883

Molecular Medicine Reports

Resveratrol ameliorates oxidative stress and inhibits aquaporin 4 expression following rat cerebral ischemia-reperfusion injury PubMed: 26458999

Chem Biol Interact

Apocynin protects against ethanol-induced gastric ulcer in rats by attenuating the upregulation of NADPH oxidases 1 and 4 PubMed: 26522475

Journal of Environmental Pathology, Toxicology and Oncology

Protective Effect of PubMed: 26349607

Journal of Immunotoxicology

Acacia ferruginea inhibits inflammation by regulating inflammatory iNOS and COX-2 PubMed: 25738525

Cancer Medicine

Circulating CD14+HLA-DR-/low myeloid-derived suppressor cells in leukemia patients with allogeneic hematopoietic stem cell transplantation: novel clinical potential strategies for the prevention and cellular therapy of graft-versus-host disease Pubmed:27109254

Journal of Natural Medicines

Anti-oxidative, anti-secretory and anti-inflammatory activities of the extract from the root bark of Lycium chinense (Cortex Lycii) against gastric ulcer in mice Pubmed:26972100

Cell Mol Immunol 

Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica Pubmed:27157496

Медицина и здравоохранение

Роль индуцибельной NO-синтазы в механизмах регуляции функциональной активности кальций-активируемых калиевых каналов коронарных сосудов у крыс, адаптированных к стрессу article:n

Graefe's Archive for Clinical and Experimental Ophthalmology

Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome pubmed:27538909

Taylor & Francis

Influences of Hyriopsis cumingii polysaccharides on mice immunosignaling molecules and T lymphocyte differentiation 09540105.2017.1306494

Molecular Vision

Mechanism of the anticataract effect of liposomal MgT in galactose-fed rats. pubmed:27440992

Journal of Natural Medicines

Anti-oxidative, anti-secretory and anti-inflammatory activities of the extract from the root bark ofLycium chinense (Cortex Lycii) against gastric ulcer in mice. pubmed:26972100

Applied Biochemistry and Biotechnology

Protective Effect of Zingiber officinale Against Dalton's Lymphoma Ascites Tumour byRegulating Inflammatory Mediator and Cytokines. pubmed:27435276

Cell Mol Neurobiol

Posttraumatic Stress Disorder Disturbs Coronary Tone and Its Regulatory Mechanisms pubmed:28676988

Microbial Immunology

Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota pubmed:28713364

Biomedicine & Pharmacotherapy

Protective effect of Averrhoa bilimbi L. fruit extract on ulcerative colitis in wistar rats via regulation of inflammatory mediators and cytokines pubmed:28531922

The Royal Society of Chemistry

Anti-ulcerogenic effect of KFP-H008 against ethanol-induced gastric ulcer via p38 MAPK/NF-κB pathway 10.1039/C7RA08879E

Acta Pharmacologica Sinica

Cis-stilbene glucoside in Polygonum multiflorum induces immunological idiosyncratic hepatotoxicity in LPS-treated rats by suppressing PPAR-γ. pubmed:28649126

Cytokine

Soy isoflavone genistein attenuates lipopolysaccharide-induced cognitive impairments in the rat via exerting anti-oxidative and anti-inflammatory effects pubmed:29102164

Molecules

Melatonin balance the autophagy and apoptosis by regulating UCP2 in the LPS-induced cardiomyopathy Pubmed:29547569

European Journal of Pharmacology 

Naringenin ameliorates learning and memory impairment following systemic lipopolysaccharide challenge in the rat Pubmed:29518393

Regulatory Toxicology and Pharmacology

Targeted inhibition of tumor survival, metastasis and angiogenesis by Acacia ferruginea mediated regulation of VEGF, inflammatory mediators, cytokine profile and … Pubmed:29678767

Pharmacological Reports

The Association between Inflammatory Markers (iNOS, HO-1, IL-33, MIP-1β) and Depression with and without Posttraumatic Stress Disorder 10.1016:j.pharep.2018.06.001

Clinical And Experimental Pharmacology And Physiology 

Diallyl sulfide alleviates cisplatin‐induced nephrotoxicity in rats via suppressing NF‐κB downstream inflammatory proteins and p53/Puma signalling pathway Pubmed:29266336


Stężenia śródbłonkowej i indukowalnej formy syntazy tlenku azotu w surowicy krwi kobiet ciężarnych palących tytoń–badania wstępne

Journal of Allergy and Clinical Immunology

Exosome swarms eliminate airway pathogens and provide passive epithelial immunoprotection through nitric oxide Pubmed: 30442371

Metabolic Brain Disease

Trigonelline protects hippocampus against intracerebral Aβ (1–40) as a model of Alzheimer's disease in the rat: insights into underlying mechanisms Pubmed: 30421246

PLoS One

Intraphagolysosomal conditions predispose to Staphylococcus epidermidis small colony variants persistence in macrophages Pubmed: 30412620

The Eurasian Journal of Medicine

Tadalafil Preserves Penile Nitric Oxide Synthase from Detrimental Effect of Paroxetine in Rats Doi: 10.5152/eurasianjmed.2018.18160

PLoS One

Macrophage expression of E3 ubiquitin ligase Grail protects mice from lipopolysaccharide-induced hyperinflammation and organ injury Pubmed: 30571701

International Journal of Environmental Research and Public Health

Influence of Active Exposure to Tobacco Smoke on Nitric Oxide Status of Pregnant Women Pubmed: 30513890

Journal of Functional Foods

Complex interaction of dietary fat and Alaskan bog blueberry supplementation influences manganese mediated neurotoxicity and behavioral impairments

Particle and Fibre Toxicology

Silica nanoparticles trigger the vascular endothelial dysfunction and prethrombotic state via miR-451 directly regulating the IL6R signaling pathway Pubmed: 30975181


ВЛИЯНИЕ ИНДУЦИБЕЛЬНОЙ NO-СИНТАЗЫ НА ТОНУС КОРОНАРНЫХ СОСУДОВ, СОКРАТИТЕЛЬНУЮ ФУНКЦИЮ МИОКАРДА И МЕХАНИЗМЫ …

Journal of Cosmetic Dermatology

Whitening effects of cosmetic formulation in the vascular component of skin pigmentation Pubmed: 31074159

regional hemodynamics and microcirculation

Benzimidazole Derivative, 2-ETH Prevents Poststressor Disorders of Coronary Vascular Tone and Myocardial Contractility

Life Sci

Cilostazol mitigates mesenteric ischemia/reperfusion-induced lung lesion: Contribution of PPAR-¦Ã, NF-¦ÊB, and STAT3 crosstalk 33310046

PLoS One

Correlation analysis of the proportion of monocytic myeloid-derived suppressor cells in colorectal cancer patients 33370317

Biotechnol Rep

Targeting NF-¦ÊB mediated cell signaling pathway and inflammatory mediators by 1, 2-diazole in A549 cells in vitro 33598414

Basic and Clinical Neuroscience

Paeonol Protects Against Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease 33995926

Fermented Foods and Microbes Related to Health

Cordyceps cicadae NTTU 868 Mycelium with The Addition of Bioavailable Forms of Magnesium from Deep Ocean Water Prevents the A¦Â40 and Streptozotocin?¡­


Ya?lanma ve Hipertansiyonda Yeni bir Endoltelyal Disfonksiyon Belirteci: ??z¨¹nebilir Lektin Benzeri Okside D¨¹?¨¹k Dansiteli Lipoprotein-1

Fermentation

Cordyceps cicadae NTTU 868 Mycelium with The Addition of Bioavailable Forms of Magnesium from Deep Ocean Water Prevents the A¦Â40 and Streptozotocin-Induced Memory Deficit via Suppressing Alzheimer¡¯s Disease Risk Factors and Increasing Magnesium Uptake of Brain

Drug Chem Toxicol

Study of cardioprotective activity of the methanolic extract of the aerial parts of Bauhinia madagascariensis compared to Bauhinia purpurea against adrenaline … 34167392

Frontiers in Cardiovascular Medicine

The Effects of Intermittent Hypoxic–Hyperoxic Exposures on Lipid Profile and Inflammation in Patients With Metabolic Syndrome 34513946

Nutrients

Erinacine A-Enriched Hericium erinaceus Mycelium Delays Progression of Age-Related Cognitive Decline in Senescence Accelerated Mouse Prone 8 (SAMP8) Mice 34684662

biomolecules

Whole-Body Cryotherapy Increases the Activity of Nitric Oxide Synthase in Older Men 34356664

Hum Exp Toxicol

Carvacrol hinders the progression of hepatic fibrosis via targeting autotaxin and thioredoxin in thioacetamide-induced liver fibrosis in rat 34155936

J Ethnopharmacol

Post-stroke treatment of storax improves long-term outcomes of stroke in rats 34343648

Phytomedicine

A multidimensional strategy for uncovering comprehensive quality markers of Schisandra chinensis (Turcz.) Baill based on pharmacodynamics and chemical …


Catalog No.

Related products for research use of Mus musculus (Mouse) Organism species

Applications (RESEARCH USE ONLY!)

RPA837Mu03

Recombinant Nitric Oxide Synthase 2, Inducible (NOS2)

Positive Control; Immunogen; SDS-PAGE; WB.

APA837Mu01

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Cell culture; Activity Assays.

RPA837Mu01

Recombinant Nitric Oxide Synthase 2, Inducible (NOS2)

Positive Control; Immunogen; SDS-PAGE; WB.

RPA837Mu02

Recombinant Nitric Oxide Synthase 2, Inducible (NOS2)

Positive Control; Immunogen; SDS-PAGE; WB.

PAA837Mu01

Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

WB; IHC; ICC; IP.

PAA837Mu02

Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

WB; IHC; ICC; IP.

PAA837Mu03

Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

WB; IHC; ICC; IP.

LAA837Mu71

Biotin-Linked Polyclonal Antibody to Nitric Oxide Synthase 2, Inducible (NOS2)

WB; IHC; ICC.

SEA837Mu

ELISA Kit for Nitric Oxide Synthase 2, Inducible (NOS2)

Enzyme-linked immunosorbent assay for Antigen Detection.

LMA837Mu

Magnetic Luminex Assay Kit for Nitric Oxide Synthase 2, Inducible (NOS2) ,etc.

Magnetic Luminex Assay for Antigen Detection.

KSA837Mu01

ELISA Kit DIY Materials for Nitric Oxide Synthase 2, Inducible (NOS2)

Main materials for "Do It (ELISA Kit) Yourself".

 

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