Cloud-clone
SKU(재고 관리 코드):PAA243Mu02
Polyclonal Antibody to Paraoxonase 1 (PON1)
Polyclonal Antibody to Paraoxonase 1 (PON1)
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
Product No.
PAA243Mu02
Organism Species
Mus musculus (Mouse).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPA243Mu02-Recombinant Paraoxonase 1 (PON1)
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Traits
Liquid
Concentration
500µg/mL
Organism Species More
Rattus norvegicus (Rat)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against PON1. It has been selected for its ability to recognize PON1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Digestive Diseases and Sciences |
Fatty Liver Is Associated with Recurrent Bacterial Infections Independent of Metabolic Syndrome PubMed: 20205513 |
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Clinica Chimica Acta |
Persistent elevation of paraoxonase-1 specific enzyme activity after weight reduction in obese non-diabetic men with metabolic syndrome PubMed: 21704607 |
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Journal of Laparoendoscopic & Advanced Surgical Techniques |
Combined Serum Proteomic and Metabonomic Profiling After Laparoscopic Sleeve Gastrectomy in Children and Adolescents Wiley: source |
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PLoS One. |
High density lipoprotein structural changes and drug response in lipidomic profiles following the long-term fenofibrate therapy in the FIELD substudy PubMed: 21887280 |
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Atherosclerosis |
Macrophage cholesterol efflux to plasma and HDL in subjects with low and high homocysteine levels: a FIELD substudy PubMed: 21696738 |
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Lipids in Health and Disease |
Beneficial effects of omega-3 fatty acids in the proteome of high-density lipoprotein proteome PubMed: PMC3480889 |
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British Journal of Nutrition |
Extra-virgin olive oil consumption reduces the age-related decrease in HDL and paraoxonase 1 anti-inflammatory activities Pubmed: 23510814 |
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Diabetes & Metabolic Syndrome |
Paraoxonase 1: A better atherosclerotic risk predictor than HDL in type 2 diabetes mellitus Pubmed: 23680251 |
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Redox Report |
Paraoxonase responses to exercise and niacin therapy in men with metabolic syndrome Pubmed:25180827 |
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Toxicol Ind Health. |
Influence of α-tocopherol and α-lipoic acid on bisphenol-A-induced oxidative damage in liver and ovarian tissue of rats Pubmed:25548375 |
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RETOS. Nuevas Tendencias en Educación Física, Deporte y Recreación |
A single session of aerobic exercise influences paraoxonase 1 activity and concentration Articulo: 345738764042 |
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PLoS One |
Plasma Protein Biomarkers of Hepatocellular Carcinoma in HCV-Infected Alcoholic Patients with Cirrhosis PubMed: 25789864 |
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Renal Failure |
Association of lipid profile with serum PON1 concentration in patients with chronic kidney disease Pubmed:26888625 |
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Pharmacological reports |
The Role of PON-1, GR, IL-18, and oxLDL in Depression With and Without Posttraumatic Stress Disorder science:article |
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Clinical and Experimental Hypertension |
Association of paraoxonase 1 (PON1) gene polymorphisms and concentration with essential hypertension pubmed:27668323 |
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Diabetes & Metabolic Syndrome: Clinical Research & Reviews |
Paraoxonase-1 is a better indicator than HDL of Atherosclerosis-A pilot Study in North Indian population pubmed:29254890 |
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Diabetes/Metabolism Research and Reviews |
A Case-control Study: The Association of Serum Paraoxonase 1 Activity and Concentration with the Development of Type 2 Diabetes Mellitus pubmed:29156090 |
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Journal of Chromatography A |
Application of a new procedure for liquid chromatography/mass spectrometry profiling of plasma amino acid-related metabolites and untargeted shotgun proteomics to identify mechanisms and biomarkers of calcific aortic stenosis S0021967317311858 |
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Pharmacological Reports |
The role of PON-1, GR, IL-18, and OxLDL in depression with and without posttraumatic stress disorder. pubmed:28623707 |
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American Journal of Food Science and Health |
Palm Wine and Orijin Bitters Severed Hyperlipidemia and Immunomodulatory Responses in Atherogenic-diet Fed Male Wistar Rats ISSN: 2381-7224 |
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Metabolic brain disease |
Individuals with autism have higher 8-Iso-PGF2α levels than controls, but no correlation with quantitative assay of Paraoxonase 1 serum levels pubmed:28808839 |
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Therapeutic Apheresis And Dialysis |
Serum Endocan Levels are Associated With Paraoxonase 1 Concentration in Patients With Chronic Kidney Disease Pubmed:29368426 |
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Biological Trace Element Research |
Effect of Aqueous Extract of Glycyrrhiza glabra on the Biochemical Changes Induced by Cadmium Chloride in Rats Pubmed: 30251228 |
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GLYCOCONJUGATE JOURNAL |
Identification a novel clinical biomarker in early diagnosis of human non-small cell lung cancer Pubmed: 30607521 |
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Hematology. |
Differentially expressed plasma proteins of β-thalassemia/hemoglobin E patients in response to curcuminoids/vitamin E antioxidant cocktails Pubmed: 30661467 |
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Proteomics Clinical Applications |
Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy Pubmed: 31162828 |
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Environment International |
Toxicity assessment due to prenatal and lactational exposure to lead, cadmium and mercury mixtures Pubmed: 31639605 |
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Nutrition, Metabolism and Cardiovascular Diseases |
Phenotypes and concentration of PON1 in cardiovascular disease: the role of nutrient intake Pubmed: 31757567 |
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Environment International |
Estimating renal and hepatic clearance rates of organophosphate esters in humans: Impacts of intrinsic metabolism and binding affinity with plasma proteins Pubmed: 31783242 |
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RESPIRATORY RESEARCH |
The HDL from septic-ARDS patients with composition changes exacerbates pulmonary endothelial dysfunction and acute lung injury induced by cecal ligation … Pubmed: 33148285 |
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CLINICAL RHEUMATOLOGY |
PON-1 haplotype (-108C> T, L55M, and Q192R) modulates the serum levels and activity PONase promoting an atherogenic lipid profile in rheumatoid arthritis patients Pubmed: 32556934 |
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respiratory research |
The adverse alterations of HDL in quality promote septic ARDS via exacerbated pulmonary endothelial dysfunction |
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J Transl Med |
Multi-omic signatures of atherogenic dyslipidaemia: pre-clinical target identification and validation in humans 33407555 |
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PLoS One |
Vitamin D status and systemic redox biomarkers in adults with obesity 30973911 |
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Oxid Med Cell Longev |
Repetitions of Strenuous Exercise Consistently Increase Paraoxonase 1 Concentration and Activity in Plasma of Average-Trained Men 34917230 |
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Catalog No. |
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