Cloud-clone
SKU(재고 관리 코드):PAA819Ca01
Polyclonal Antibody to Parathyroid Hormone Related Protein (PTHrP)
Polyclonal Antibody to Parathyroid Hormone Related Protein (PTHrP)
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
Product No.
PAA819Ca01
Organism Species
Canis familiaris; Canine (Dog).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPA819Ca01-Recombinant Parathyroid Hormone Related Protein (PTHrP)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
500µg/mL
Organism Species More
Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against PTHrP. It has been selected for its ability to recognize PTHrP in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Clinical and Experimental Metastasis |
Characterization of a new renal cell carcinoma bone metastasis mouse model PubMed: 20443133 |
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Stem Cells and Development |
Temporal activation of β-catenin signaling in the chondrogenic process of mesenchymal stem cells affects the phenotype of the cartilage generated. PubMed: 22133004 |
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International journal of biological sciences |
PTHrP Expression in Human MDA-MB-231 Breast Cancer Cells Is Critical for Tumor Growth and Survival and Osteoblast Inhibition PubMed: PMC3753447 |
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Investigational New Drugs |
Tetrahydrofurofuran-type lignans inhibit breast cancer-mediated bone destruction by blocking the vicious cycle between cancer cells, osteoblasts and osteoclasts Pubmed: 23673814 |
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Toxicology and Applied Pharmacology |
Betulinic acid, a bioactive pentacyclic triterpenoid, inhibits skeletal-related events induced by breast cancer bone metastases and treatment Pubmed:24463094 |
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Arch Gynecol Obstet. |
Calcitonin gene-and parathyroid hormone-related peptides in normotensive and preeclamptic pregnancies: a nested case–control study Pubmed:24943060 |
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PLoS One |
15-Deoxy-Δ12, 14-Prostaglandin J2 Inhibits Osteolytic Breast Cancer Bone Metastasis and Estrogen Deficiency-Induced Bone Loss PubMed: 25859665 |
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Endocrinology |
A role for the calcitonin receptor to limit bone loss during lactation in female mice by inhibiting osteocytic osteolysis PubMed: 26135836 |
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Tumour Biol |
Osteopontin expression in co-cultures of human squamous cell carcinoma-derived cells and osteoblastic cells and its effects on the neoplastic cell phenotype and osteoclastic activation. Pubmed:27312487 |
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35 |
Hedgehog signaling in bone regulates whole-body energy metabolism through a bone–adipose endocrine relay mediated by PTHrP and adiponectin pubmed:27740628 |
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Bone |
Lactation induces increases in the RANK/RANKL/OPG system in maxillary bone Pubmed:29382610 |
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International Journal of Molecular Sciences |
A Diet Rich in Fish Oil and Leucine Ameliorates Hypercalcemia in Tumour-Induced Cachectic Mice Pubmed: 31600911 |
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Journal of Orthopaedic Surgery and Research |
Identification of a potential gene target for osteoarthritis based on bioinformatics analyses Pubmed: 32571421 |
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International Immunopharmacology |
Parathyroid hormone related protein (PTHrP)-mediated hypercalcemia in malignancy associated with anti-PD-1 immune checkpoint inhibitor treatment and related … |
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Паратиреоидный гормон-родственный протеин как предиктор развития мочекаменной болезни |
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Cell Death Dis |
Extracellular vesicles-released parathyroid hormone-related protein from Lewis lung carcinoma induces lipolysis and adipose tissue browning in cancer ¡ 33510128 |
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Sci Rep |
Effects of whole-body vibration training in a cachectic C26 mouse model 34732809 |
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Acta Physiologica |
The acute adaptation of renal phosphate transporters in the murine kidney to oral phosphate intake requires multiple signals Pubmed:35334154 |
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Catalog No. |
Related products for research use of Canis familiaris; Canine (Dog) Organism species |
Applications (RESEARCH USE ONLY!) |
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RPA819Ca01 |
Positive Control; Immunogen; SDS-PAGE; WB. |
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PAA819Ca01 |
Polyclonal Antibody to Parathyroid Hormone Related Protein (PTHrP) |
WB; IHC; ICC; IP. |
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LAA819Ca71 |
Biotin-Linked Polyclonal Antibody to Parathyroid Hormone Related Protein (PTHrP) |
WB; IHC; ICC. |
|
MAA819Ca21 |
Monoclonal Antibody to Parathyroid Hormone Related Protein (PTHrP) |
WB; IHC; ICC; IP. |
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