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SKU(재고 관리 코드):PAC845Hu01

Polyclonal Antibody to Renalase (RNLS)

Polyclonal Antibody to Renalase (RNLS)

UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL;1:250-1000
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

PAC845Hu01

Organism Species

Homo sapiens (Human).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPC845Hu01-Recombinant Renalase (RNLS)

Buffer Formulation

PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.

Traits

Liquid

Concentration

500µg/ml

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against RNLS. It has been selected for its ability to recognize RNLS in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;1:250-1000
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Pol Arch Med Wewn.

Renalase, kidney function, and markers of endothelial dysfunction in renal transplant recipients Cartelcolor: source

Angiology

Renalase, Stroke, and Hypertension in Hemodialyzed Patients PubMed: 22583169

Peritoneal dialysis international

Renalase in peritoneal dialysis patients is not related to blood pressure, but to dialysis vintage. Pdiconnect: Source

Archives of Medical Science

Vascular adhesion protein-1 and renalase in regard to diabetes in hemodialysis patients PubMed: PMC3542495

Renal Failure

Circulating Levels of Renalase, Norepinephrine, and Dopamine in Dialysis Patients Pubmed: 23530612

Borgis - Postepy Nauk Medycznych

VAP-1 in chronic kidney disease and diabetic kidney disease Czytelniamedyczna: Source

Journal of Basic and Clinical Physiology and Pharmacology

The relationship between dopamine and renalase in type 2 diabetic patients with and without diabetic nephropathy Pubmed: 15365253

Exp Biol Med (Maywood).

Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients. Pubmed: 24599883

Kidney Blood Press Res.

Renalase, a novel enzyme involved in blood pressure regulation, is related to kidney function but not to blood pressure in hemodialysis patients. Pubmed: 22539018

Nephrology Dialysis Transplantation

Renalase in hypertension and kidney disease Oxfordjournals: Source

Lipids in Health and Disease

Markers of increased cardiovascular risk in patients with chronic kidney disease Biomedcentral:Source

Research & Experimental?

Plasma and urine renalase levels and activity during the recovery of renal function in kidney transplant recipients Pubmed:24599883

Pediatr Nephrol

Normal values for urine renalase excretion in children Pubmed:25060760

J Am Soc Hypertens.

Low plasma renalase concentration in hypertensive patients after surgical repair of coarctation of aorta Pubmed:25064768

Cardiology.

Effect of salt intake and potassium supplementation on urinary renalase and serum dopamine levels in Chinese adults Pubmed:25824645

J Am Soc Hypertens

Circulating renalase, catecholamines, and vascular adhesion PubMed: 26403854

Indian Pediatr

Renalase levels in children with solitary functioning kidney PubMed: 26713989

Oxford Journals

SP321 RENALASE, RENAL FUNCTION AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS Content: 30

journal of hypertension

PP.27.07: PREHYPERTENSIVE ALTERATIONS OF ARTERIAL AND VENOUS REACTIVITY IN A RAT POLYCYSTIC OVARY SYNDROME MODEL. EFFECTS OF PARALLEL VITAMIN D3 ADMINISTRATION Jhypertension: Abstract

journal of hypertension

PP.27.06: RENALASE, RENAL FUNCTION AND BIOMARKERS OF ENDOTHELIAL DYSFUNCTION IN CHRONIC KIDNEY DISEASE PATIENTS. Jhypertension: Abstract

journal of hypertension

PP.27.04: ENDOTHELIAL DYSFUNCTION AND ARTERIAL HYPERTENSION IN THE WORKING POPULATION (MERIDIAN STUDY). Jhypertension: Abstract

Curr Vasc Pharmacol.

Renalase is Removed by Kidneys and During Dialysis – Excess Related to CKD Complications? PubMed: 25515790

Kidney Blood Press Res

Effects of Renin-Angiotensin System Inhibitors on Renal Expression of Renalase in Sprague-Dawley Rats Fed With High Salt Diet PubMed: 26619289

PLoS One

Serum Renalase Levels Correlate with Disease Activity in Lupus Nephritis PubMed: 26431044

J Hum Hypertens

Plasma renalase concentration before and after radiofrequency renal denervation in patients with resistant hypertension PubMed: 26310184

Nephrology (Carlton)

Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography. pubmed:27778420

Nephrol Dial Transplant

PLASMA RENALASE CONCENTRATION BEFORE AND AFTER RADIOFREQUENCY RENAL DENERVATION IN PATIENTS WITH RESISTANT HYPERTENSION: PRELIMINARY RESULTS content:31

Renal Failure

Increased serum renalase in hemodialysis patients: is it related to left ventricular hypertrophy? pubmed:27416751

Enhanced biocompatible and hemocompatible nano/micro porous surface as a biological scaffold for functionalizational and biointegrated implants

High-performance Liquid Chromatography Measured Metabolites of EndogenousCatecholamines and Their Relations to Chronic Kidney Disease and High Blood Pressure in Heart Transplant Recipients. pubmed:27496485

PLOS ONE

Online Haemodiafiltration Improves Inflammatory State in Dialysis Patients: A Longitudinal Study. pubmed:27783636

Advances in Experimental Medicine and Biology

Renalase in Children with Glomerular Kidney Diseases chapter:10.1007

Kidney & Blood Pressure Research

Plasma Renalase is Not Associated with Blood Pressure and Brachial-Ankle Pulse Wave Velocity in Chinese Adults With Normal Renal Function 452587

BMC nephrology

Rs10887800 renalase gene polymorphism influences the level of circulating renalase in patients undergoing hemodialysis but not in healthy controls pubmed:28372594

Nefrología (English Edition)

Increased serum renalase in peritoneal dialysis patients: Is it related to cardiovascular disease risk pubmed:28160962

Clinical Interventions in Aging

Age influence on renalase and catecholamines concentration in hypertensive patients, including maintained dialysis pubmed:27822026

International Journal of Clinical and Experimental Medicine

Aumento de renalasa sérica en pacientes de diálisis peritoneal:¿ está relacionado con el riesgo de enfermedad cardiovascular? 10.1016:j.nefro.2016.11.013

PLoS One

Relationship between microRNA-146a expression and plasma renalase levels in hemodialyzed patients pubmed:28614373

Annals of Agricultural and Environmental Medicine

Levels of renalase and advanced oxidation protein products with regard to catecholamines in haemodialysed patients pubmed:28954489

Angiology

Endocan Concentration in Patients With Primary Hypertension pubmed:29084442

Journal of Hypertension

RENALASE PLASMA CONCENTRATION BEFORE AND AFTER RADIOFREQUENCY RENAL DENERVATION IN PATIENTS WITH RESISTANT HYPERTENSION 10.1097/01.hjh.0000523893.07419.ae

International journal of molecular sciences

Renalase Protects against Renal Fibrosis by Inhibiting the Activation of the ERK Signaling Pathways pubmed:28448446

Journal of sports medicine and physical fitness

Transient changes in serum renalase concentration during long-distance running: The case of an amateur runner under continuous training 10.7600/jpfsm.6.159

Scientific Reports

Synergistic effect of renalase and chronic kidney disease on endothelin-1 in patients with coronary artery disease‒a cross-sectional study Pubmed:29743680

Life Sciences

Influence of acute exercise on renalase and its regulatory mechanism Pubmed:30056018

Experimental Eye Research

Quantitative analysis of hydroxyapatite-binding plasma proteins in genotyped individuals with late-stage age-related macular degeneration Pubmed:29580721

Rapid Communications in Mass Spectrometry

A new method for quantitative determination of renalase based on mass‐spectrometry determination of a proteotypic peptide labeled with stable isotopes 10.1002:rcm.8167

International Urology and Nephrology

Renalase contributes to protection against renal fibrosis via inhibiting oxidative stress in rats Pubmed:29476431

Pediatric Cardiology

Serum Renalase Levels in Adolescents with Primary Hypertension Pubmed:29748702

Postepy w Kardiologii Interwencyjnej

Atorvastatin facilitates protection against contrast-induced nephropathy in patients undergoing coronary angiography via humoral mediators rather than … Pubmed:30008773


High urinary kidney injury molecule type 1 level is associated with 12-month adverse cardiovascular events in patients with coronary artery disease publication:324522368

Journal of Clinical Medicine

Serum Renalase Levels Are Predicted by Brain-Derived Neurotrophic Factor and Associated with Cardiovascular Events and Mortality after Percutaneous Coronary … Pubmed: 30424498

Archives of disease in childhood

GP23 Percutaneous closure of patent ductus arteriosus: single center experience

Archives of disease in childhood

GP25 Comparison of associations and outcomes of prenatally and postnatally diagnosed right aortic arch: south wales' experience

Archives of disease in childhood

GP24 Serum renalase levels in adolescents with primary hypertension

Disease Markers

Association of Plasma Renalase and Left Ventricle Mass Index in Heart Failure Patients Stratified to the Category of the Ejection Fraction: A Pilot Study Pubmed: 31737132

EXPERIMENTAL BIOLOGY AND MEDICINE

The role of urinary renalase on early-stage renal damage in Chinese adults with primary hypertension Pubmed: 32102561

FEBS Open Bio

Moderate‐intensity exercise increases renalase levels in the blood and skeletal muscle of rats Pubmed: 32053739

current medical research and opinion

The partnership between renalase and ejection fraction as a risk factor for increased cardiac remodeling biomarkers in chronic heart failure patients Pubmed: 32297799

Dovepress

Association of Serum Renalase Levels and Renalase rs10887800 Polymorphism with Unstable Angina Pectoris Patients Having Metabolic Syndrome Pubmed: 32982355

学位论文

Nikotinamidadenindinukleotid-Blutplasmawerte sind unabhängig vom kalendarischen und vaskulären Alter in einer Normalkohorte aus der Region Halle-Saalekreis

Life

Circulating Renalase as Predictor of Renal and Cardiovascular Outcomes in Pre-Dialysis CKD Patients: A 5-Year Prospective Cohort Study 33800219


Edited by: Background: Renalase has been implicated in chronic heart failure (CHF); however, nothing is known about renalase discriminatory ability and prognostic …


Catalog No.

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