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SKU(재고 관리 코드):PAA567Rb51

Polyclonal Antibody to S100 Calcium Binding Protein B (S100B)

Polyclonal Antibody to S100 Calcium Binding Protein B (S100B)

UOM
Concentration
Organism species

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

Product No.

PAA567Rb51

Organism Species

Oryctolagus cuniculus (Rabbit).

Source

Polyclonal antibody preparation

Host

Guinea pig

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

APC

Immunogen

n/a

Buffer Formulation

PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

Traits

Liquid

Concentration

500µg/mL

Organism Species More

Homo sapiens (Human), Mus musculus (Mouse), Rattus norvegicus (Rat)

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a cavia polyclonal antibody raised against S100B. It has been selected for its ability to recognize S100B in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.2-2µg/mL;1:250-2500
Immunohistochemistry: 5-20µg/mL;1:25-100
Immunocytochemistry: 5-20µg/mL;1:25-100
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Epilepsia

Protective effects of naloxone in two-hit seizure model PubMed: 19674055

Journal of Neurotrauma

The Anti-Inflammatory and Neuroprotective Effects of Ghrelin in Subarachnoid Hemorrhage-Induced Oxidative Brain Damage in Rats Liebert: 20091210

Food and Chemical Toxicology

Sub-acute effects of diazinon on biochemical indices and specific biomarkers in rats: Protective effects of crocin and safranal PubMed: 20637253

20

Melatonin treatment protects against spinal cord injury induced functional and biochemical changes in rat urinary bladder Wiley: source

Neuroscience Letters

A preliminary study of the effects of ulinastatin on early postoperative cognition function in patients undergoing abdominal surgery Pubmed: 23422155

Genes Cells

Induction of receptor for advanced glycation end products by insufficient leptin action triggers pancreatic β-cell failure in type 2 diabetes. Pubmed: 23410183

J Craniofac Surg.

The Experiment Research of Neuroprotection of Hypoperfusion Postconditioning on Cerebral Ischemia Pubmed:25006960

Int J Mol Sci

The effect of electroporation of a lyotroic liquid crystal Genistein-based formulation in the recovery of murine melanoma lesions PubMed: 26184156

Mol Neurobiol

The Severity of Cecal Ligature and Puncture-Induced Sepsis Correlates with the Degree of Encephalopathy, but the Sepsis Does Not Lead to Acute Activation of Spleen Lymphocytes in Mice PubMed: 26081155

Pediatria i Medycyna Rodzinna

Stężenie białka S100B w surowicy krwi u młodzieży z omdleniami yadda:60e5630d0ac1

中国临床药理学与治疗学

右美托咪定对脑膜瘤切除术患者血清S100β 蛋白及神经元特异性烯醇化酶的影响 article:9794

Eur J Pharmacol. 

Development of an experimental rat model of hyperammonemic encephalopathy and evaluation of the effects of rifaximin Pubmed:26980242

Journal For Neurovirology

Soluble TLR2 and 4 concentrations in cerebrospinal fluid in HIV/SIV-relatedneuropathological conditions. pubmed:27882497

Neurourol Urodyn

Functional and structural changes of the urinary bladder following spinal cord injury; treatment with alpha lipoic acid pubmed:27490041

cellular physiology and biochemistry

Hydrogen-Rich Saline Attenuates Brain Injury Induced by Cardiopulmonary Bypass and Inhibits Microvascular Endothelial Cell Apoptosis Via the PI3K/Akt/GSK3β … pubmed:29040978

Biomedicine & pharmacotherapy

Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms pubmed:28061403

Cellular Physiology and Biochemistry

Activated Α7nachr Improves Postoperative Cognitive Dysfunction and Intestinal Injury Induced by Cardiopulmonary Bypass in Rats: Inhibition of the Proinflammatory … Pubmed:29672286

Brain Research

Intra-arterial human urinary kallidinogenase alleviates brain injury in rats with permanent middle cerebral artery occlusion through PI3K/AKT/FoxO1 signaling pathway Pubmed:29510144

Neurochemical Research

Protective Effects of Cornel Iridoid Glycoside in Rats After Traumatic Brain Injury Pubmed:29492766

Biochemical and Biophysical Research Communications

C6 glioma-conditioned medium induces malignant transformation of mesenchymal stem cells: Possible role of S100B/RAGE pathway Pubmed:29050939

Journal of the Neurological Sciences

S100B, NSE and MMP-9 fail to predict neurologic outcome while elevated S100B associates with milder initial clinical presentation after aneurysmal subarachnoid … Pubmed:29801873

Biochemistry and Cell Biology

Ectopic expression of Miro 1 ameliorates seizures and inhibits hippocampal neurodegeneration in a mouse model of pilocarpine epilepsy Pubmed:29365285


S100B as a potential biomarker for concussion in male and female collegiate rugby athletes :

Indian Journal of Psychiatry

Serum S100B levels in patients with depression

Evidence-Based Complementary and Alternative Medicine

Naomaitai Ameliorated Brain Damage in Rats with Vascular Dementia by PI3K/PDK1/AKT Signaling Pathway

Brain Sciences

Extracellular S100β Disrupts Bergman Glia Morphology and Synaptic Transmission in Cerebellar Purkinje Cells Pubmed: 31013844

Medicina

The Administration of the New Pyrimidine Derivative—4-{2-[2-(3, 4-Dimethoxyphenyl)-Vinyl]-6-Ethyl-4-Oxo-5-Phenyl-4H-Pyrimidine-1-Il} Benzsulfamide Restores the …

ACTA NEUROBIOLOGIAE EXPERIMENTALIS

Neuroprotective effect of poly (lactic-co-glycolic acid) nanoparticle-bound brain-derived neurotrophic factor in a permanent middle cerebral artery occlusion … Pubmed: 32214270

Stem Cells International

Exosomes of Antler Mesenchymal Stem Cells Improve Postoperative Cognitive Dysfunction in Cardiopulmonary Bypass Rats through Inhibiting the TLR2 … Pubmed: 32300366

Neurocritical Care

Biomarkers of Neurological Outcome After Aneurysmal Subarachnoid Hemorrhage as Early Predictors at Discharge from an Intensive Care Unit Pubmed: 32978732

European Review for Medical and Pharmacological Sciences

Neuroprotective effect of CTRP3 overexpression against sevoflurane anesthesia-induced cognitive dysfunction in aged rats through activating AMPK/SIRT1 and … Pubmed: 32432773


ИЗУЧЕНИЕ ЦЕРЕБРОПРОТЕКТОРНОГО ДЕЙСТВИЯ ПРЕПАРАТОВ РАЗЛИЧНЫХ ФАРМАКОЛОГИЧЕСКИХ ГРУПП В УСЛОВИЯХ …

Scientific Reports

Potential biomarkers of childhood brain tumor identified by proteomics of cerebrospinal fluid from extraventricular drainage (EVD) 33469081

Crit Care

Serum biomarkers and cerebral autoregulation as early warnings of delayed cerebral ischemia risk in patients after aneurysmal subarachnoid haemorrhage 27885969

Transl Psychiatry

Increased GFAP concentrations in the cerebrospinal fluid of patients with unipolar depression 34021122

Biochimie

Neuroprotective effect of 6-hydroxy-2, 2, 4-trimethyl-1, 2-dihydroquinoline mediated via regulation of antioxidant system and inhibition of inflammation and apoptosis in?¡­ 33964368

Int J Neuropsychopharmacol

High S100B levels predict antidepressant response in patients with major depression even when considering inflammatory and metabolic markers Pubmed:35176771

Metab Brain Dis

1-benzoyl-6-hydroxy-2, 2, 4-trimethyl-1, 2-dihydroquinoline exerts a neuroprotective effect and normalises redox homeostasis in a rat model of cerebral ischemia … Pubmed:35201554

PLoS One

Neuroprotective effect of sodium alginate against chromium-induced brain damage in rats Pubmed:35421180

International Journal of Molecular Sciences

Sepsis Encephalopathy Is Partly Mediated by miR370-3p-Induced Mitochondrial Injury but Attenuated by BAM15 in Cecal Ligation and Puncture Sepsis Male Mice Pubmed:35628259

Authorea

THE EVALUATION OF MEDULLA SPINALIS PERFUSION AT MODERATE HYPOTHERMIA WITH PATIENTS WHO UNDERGO ANTEGRADE SELECTIVE CEREBRAL …


EPIDEMIOLOGIA, DETERMINANTELE ȘI PREDICȚIA ACCIDENTULUI VASCULAR CEREBRAL ISCHEMIC LA COPII


Catalog No.

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Applications (RESEARCH USE ONLY!)

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WB; IHC; ICC.

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WB; IHC; ICC; IF.

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Enzyme-linked immunosorbent assay for Antigen Detection.

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Magnetic Luminex Assay for Antigen Detection.

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ELISA Kit DIY Materials for S100 Calcium Binding Protein B (S100B)

Main materials for "Do It(ELISA Kit) Yourself"

 

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