Cloud-clone
SKU(재고 관리 코드):PAC864Hu01
Polyclonal Antibody to Sclerostin (SOST)
Polyclonal Antibody to Sclerostin (SOST)
Western blotting: 0.5-2µg/mL;1:150-600
;Immunohistochemistry: 5-20µg/mL;1:15-60
;Immunocytochemistry: 5-20µg/mL;1:15-60
;Optimal working dilutions must be determined by end user.
Product No.
PAC864Hu01
Organism Species
Homo sapiens (Human).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPC864Hu01-Recombinant Sclerostin (SOST)
Buffer Formulation
0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Traits
Liquid
Concentration
0.31mg/ml
Organism Species More
Sus scrofa; Porcine (Pig)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against SOST. It has been selected for its ability to recognize SOST in immunohistochemical staining and western blotting.
USAGE
Western blottin:g: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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Life Sciences |
Exendin-4 Increases Bone Mineral Density in Type 2 Diabetic OLETF Rats Potentially Through the Down-Regulation of SOST/Sclerostin in Osteocytes PubMed: 23357248 |
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Calcified Tissue International |
Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes Pubmed: 23247536 |
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Arthritis Res Ther. |
Serum Sclerostin in Adult High-Activity Patients with Juvenile Idiopathic Arthritis Pubmed:Pmc4236454 |
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Korean J Intern Med |
Early effects of tumor necrosis factor inhibition on bone homeostasis after soluble tumor necrosis factor receptor use Pubmed:Pmc4219971 |
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Journal of Bone and Mineral Research |
The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5 Pubmed:25640331 |
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FASEB J. |
DMP-1-mediated PubMed: 26481310 |
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Pharmacology |
Effect of Mirtazapine on Rat Bone Tissue after Orchidectomy PubMed: 25871861 |
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European Journal of Pharmacology |
The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism Pubmed:29428468 |
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EFFECTS OF DISEASE-MODIFYING ANTIRHEUMATIC DRUG TREATMENT ON PERIARTICULAR BONE REMODELING IN RHEUMATOID AND PSORIATIC … : |
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Journal of Clinical and Translational Endocrinology |
Dobesity: relationship between vitamin d deficiency, obesity and sclerostin as a novel biomarker of bone metabolism |
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JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY |
Circulating Osteocyte‐Related Biomarkers (vitamin D, sclerostin, dickkopf-1), hepcidin, and oxidative stress markers in early breast cancer: their impact in … Pubmed: 33065276 |
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Oxid Med Cell Longev |
Long-Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats 34373766 |
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Catalog No. |
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Applications (RESEARCH USE ONLY!) |
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