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SKU(재고 관리 코드):PAC864Mu01

Polyclonal Antibody to Sclerostin (SOST)

Polyclonal Antibody to Sclerostin (SOST)

UOM
Concentration
Organism species

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

Product No.

PAC864Mu01

Organism Species

Mus musculus (Mouse).

Source

Polyclonal antibody preparation

Host

Rabbit

Potency

n/a

Ig Type

IgG

Purification

Antigen-specific affinity chromatography followed by Protein A affinity chromatography

Label

None

Immunogen

RPC864Mu01-Recombinant Sclerostin (SOST)

Buffer Formulation

0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.

Traits

Liquid

Concentration

0.6mg/ml

Organism Species More

n/a

Applications

WB; IHC; ICC; IP.

If the antibody is used in flow cytometry, please check FCM antibodies.

UOM

20µl 100µl 200µl 1ml 10ml

SPECIFITY

The antibody is a rabbit polyclonal antibody raised against SOST. It has been selected for its ability to recognize SOST in immunohistochemical staining and western blotting.

USAGE

Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.

STORAGE

Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine

Citations

Life Sciences

Exendin-4 Increases Bone Mineral Density in Type 2 Diabetic OLETF Rats Potentially Through the Down-Regulation of SOST/Sclerostin in Osteocytes PubMed: 23357248

Calcified Tissue International

Acute effects of glucocorticoids on serum markers of osteoclasts, osteoblasts, and osteocytes Pubmed: 23247536

Arthritis Res Ther.

Serum Sclerostin in Adult High-Activity Patients with Juvenile Idiopathic Arthritis Pubmed:Pmc4236454

Korean J Intern Med

Early effects of tumor necrosis factor inhibition on bone homeostasis after soluble tumor necrosis factor receptor use Pubmed:Pmc4219971

Journal of Bone and Mineral Research

The Anti-Osteoanabolic Function of Sclerostin is Blunted in Mice Carrying a High Bone Mass Mutation of Lrp5 Pubmed:25640331

FASEB J.

DMP-1-mediated PubMed: 26481310

Pharmacology

Effect of Mirtazapine on Rat Bone Tissue after Orchidectomy PubMed: 25871861

European Journal of Pharmacology

The effect of levetiracetam on rat bone mineral density, bone structure and biochemical markers of bone metabolism Pubmed:29428468


EFFECTS OF DISEASE-MODIFYING ANTIRHEUMATIC DRUG TREATMENT ON PERIARTICULAR BONE REMODELING IN RHEUMATOID AND PSORIATIC … :

Journal of Clinical and Translational Endocrinology

Dobesity: relationship between vitamin d deficiency, obesity and sclerostin as a novel biomarker of bone metabolism

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Circulating Osteocyte‐Related Biomarkers (vitamin D, sclerostin, dickkopf-1), hepcidin, and oxidative stress markers in early breast cancer: their impact in … Pubmed: 33065276

Oxid Med Cell Longev

Long-Term Administration of Abacavir and Etravirine Impairs Semen Quality and Alters Redox System and Bone Metabolism in Growing Male Wistar Rats 34373766


Catalog No.

Related products for research use of Mus musculus (Mouse) Organism species

Applications (RESEARCH USE ONLY!)

RPC864Mu01

Recombinant Sclerostin (SOST)

Positive Control; Immunogen; SDS-PAGE; WB.

RPC864Mu02

Recombinant Sclerostin (SOST)

Positive Control; Immunogen; SDS-PAGE; WB.

PAC864Mu01

Polyclonal Antibody to Sclerostin (SOST)

WB; IHC; ICC; IP.

PAC864Mu02

Polyclonal Antibody to Sclerostin (SOST)

WB; IHC; ICC; IP.

SEC864Mu

ELISA Kit for Sclerostin (SOST)

Enzyme-linked immunosorbent assay for Antigen Detection.

SCC864Mu

CLIA Kit for Sclerostin (SOST)

Chemiluminescent immunoassay for Antigen Detection.

LMC864Mu

Magnetic Luminex Assay Kit for Sclerostin (SOST) ,etc.

Magnetic Luminex Assay for Antigen Detection.

 

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