Cloud-clone
SKU(재고 관리 코드):PAE912Ra01
Polyclonal Antibody to Sirtuin 1 (SIRT1)
Polyclonal Antibody to Sirtuin 1 (SIRT1)
Western blotting: 0.5-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
Product No.
PAE912Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Polyclonal antibody preparation
Host
Rabbit
Potency
n/a
Ig Type
IgG
Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Label
None
Immunogen
RPE912Ra01-Recombinant Sirtuin 1 (SIRT1)
Buffer Formulation
PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Traits
Liquid
Concentration
0.31mg/ml
Organism Species More
Homo sapiens (Human), Mus musculus (Mouse)
Applications
WB; IHC; ICC; IP.
If the antibody is used in flow cytometry, please check FCM antibodies.
UOM
20µl 100µl 200µl 1ml 10ml
SPECIFITY
The antibody is a rabbit polyclonal antibody raised against SIRT1. It has been selected for its ability to recognize SIRT1 in immunohistochemical staining and western blotting.
USAGE
Western blotting: 0.01-2µg/mL;
Immunohistochemistry: 5-20µg/mL;
Immunocytochemistry: 5-20µg/mL;
Optimal working dilutions must be determined by end user.
STORAGE
Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
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Magazine |
Citations |
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PLoS One. |
SIRT1 Gene Polymorphisms Affect the Protein Expression in Cardiovascular Diseases Plos: Source |
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PLOS ONE |
A Novel Role for SIRT-1 in L-Arginine Protection against STZ Induced Myocardial Fibrosis in Rats Pubmed:25501750 |
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Journal of Alzheimer's Disease |
Serum miR-206 and miR-132 as Potential Circulating Biomarkers for Mild Cognitive Impairment Pubmed:25589731 |
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Respirology |
Increases in peripheral SIRT1: A new biological characteristic of asthma PubMed: 26040995 |
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PLOS ONE |
A Remarkable Age-Related Increase in SIRT1 Protein Expression against Oxidative Stress in Elderly: PubMed: 25785999 |
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Endocrine |
Changes of serum Mir-217 and the correlation with the severity in type 2 diabetes patients with different stages of diabetic kidney disease. pubmed:27522360 |
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Naunyn Schmiedebergs Arch Pharmacol |
The potential curative effect of rebamipide in hepatic ischemia/reperfusion injury pubmed:28361247 |
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International journal of cardiology |
A sirtuin 1/MMP2 prognostic index for myocardial infarction in patients with advanced coronary artery disease pubmed:28043667 |
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International Journal of Cardiology |
Serum concentrations and gene expression of sirtuin 1 in healthy and slightly overweight subjects after caloric restriction or resveratrol supplementation: A randomized trial pubmed:28029409 |
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Hepatology International |
Association of SIRT1 gene polymorphism and its expression for the risk of alcoholic fatty liver disease in the Han population pubmed:29189974 |
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Toxicology and Applied Pharmacology |
Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) pubmed:28974454 |
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Chemico-biological Interactions |
Magnolol protects pancreatic β-cells against methylglyoxal-induced cellular dysfunction pubmed:28919305 |
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Nutrients |
Gene Expression of Sirtuin-1 and Endogenous Secretory Receptor for Advanced Glycation End Products in Healthy and Slightly Overweight Subjects after … Pubmed:30037068 |
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Experimental Gerontology |
Specific alterations in the circulating levels of the SIRT1, TLR4, and IL7 proteins in patients with dementia Pubmed:30071285 |
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Kidney and Blood Pressure Research |
The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy Pubmed: 30504713 |
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Journal of International Medical Research |
Serum and follicular fluid levels of sirtuin 1, sirtuin 6, and resveratrol in women undergoing fertilization: an observational, clinical study Pubmed: 30556451 |
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BioMed Research International |
Centella asiatica Prevents Increase of Hippocampal Tumor Necrosis Factor-Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of Chronic … |
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学位论文 |
Influência do tratamento da doença periodontal na sirtuína 1 e na lectina ligadora de manose em indivíduos com doença arterial coronária |
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Journal of Physics D: Applied Physics |
Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility |
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Journal of Geriatric Oncology |
Serum biomarkers for predicting overall survival and early mortality in older patients with metastatic solid tumors Pubmed: 30952517 |
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Biomed Research International |
Prevents Increase of Hippocampal Tumor Necrosis Factor-α Independently of Its Effect on Brain-Derived Neurotrophic Factor in Rat Model of … Pubmed: 30956976 |
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Journal of Diabetes and its Complications |
Vasohibin-1 in T2DM with different UACR |
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Clinical Interventions in Aging |
The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and αKlotho in Patients with End-Stage Kidney Disease on Maintenance Hemodialysis Pubmed: 32214805 |
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Compr Psychiatry |
Crocin alleviates schizophrenia-like symptoms in rats by upregulating silent information regulator-1 and brain derived neurotrophic factor Pubmed: 33045669 |
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Сибирский федеральный университет |
Влияние гречневой крупы на сиртуиновую активность у подопытных животных в эксперименте |
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Journal of Cereal Science |
Dietary buckwheat enhances sirtuin1 without calorie restriction |
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Clin Interv Aging |
Molecular Changes in Circulating microRNAs' Expression and Oxidative Stress in Adults with Mild Cognitive Impairment: A Biochemical and Molecular Study 33447019 |
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Antioxidants |
The Effect of Repeated Whole-Body Cryotherapy on Sirt1 and Sirt3 Concentrations and Oxidative Status in Older and Young Men Performing Different Levels of?¡ 33396247 |
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Int Urol Nephrol |
Evaluation of sirtuin 1 (SIRT1) levels in autosomal dominant polycystic kidney disease 33864594 |
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Neurochem Int |
Dimethyl fumarate abridged tauo-/amyloidopathy in a D-Galactose/ovariectomy-induced Alzheimer's-like disease: Modulation of AMPK/SIRT-1, AKT/CREB/BDNF, AKT ¡ 34052296 |
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Toxicol Appl Pharmacol |
Prasugrel anti-ischemic effect in rats: Modulation of hippocampal SUMO2/3-IкBα/Ubc9 and SIRT-1/miR-22 trajectories 34174262 |
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Food Chem |
Buckwheat-enriched diet alleviates bisphenol A mediated oxidative stress via modulation of sirtuin 1 and antioxidant status in experimental rats 34763933 |
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Life Sci |
Novel mechanistic insights towards the repositioning of alogliptin in Parkinson's disease 34774622 |
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Int J Mol Sci |
Intralesional Infiltrations of Arteriosclerotic Tissue Cells-Free Filtrate Reproduce Vascular Pathology in Healthy Recipient Rats Pubmed:35163435 |
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J Clin Med |
Effects of Coffee on Sirtuin-1, Homocysteine, and Cholesterol of Healthy Adults: Does the Coffee Powder Matter? Pubmed:35683374 |
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Cell & Bioscience |
OGT Protects Skeletal Muscle From Damage Through SIRT1 O-GlcNAcylation During Cold Stress |
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Catalog No. |
Related products for research use of Rattus norvegicus (Rat) Organism species |
Applications (RESEARCH USE ONLY!) |
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RPE912Ra01 |
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RPE912Ra02 |
Positive Control; Immunogen; SDS-PAGE; WB. |
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PAE912Ra01 |
WB; IHC; ICC; IP. |
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PAE912Ra02 |
WB; IHC; ICC; IP. |
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MAE912Ra21 |
WB; IHC; ICC; IP. |
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SEE912Ra |
Enzyme-linked immunosorbent assay for Antigen Detection. |
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SCE912Ra |
Chemiluminescent immunoassay for Antigen Detection. |
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LME912Ra |
Magnetic Luminex Assay for Antigen Detection. |
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