PPAR alpha(Phospho Ser21) Rabbit Polyclonal Antibody

Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand| the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcription. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids.|online information:Peroxisome proliferator-activated receptor entry|Belongs to the nuclear hormone receptor family. NR1 subfamily.|Contains 1 nuclear receptor DNA-binding domain.|subunit:Heterodimer with the retinoid X receptor. Interacts with NCOA3 and NCOA6 coactivators| leading to a strong increase of transcription of target genes. Also interacts with PPARBP coactivator in vitro. Interacts with AKAP13.|tissue specificity:Skeletal muscle| liver| heart and kidney.|

The PPAR ALPHA(PHOSPHO SER21) Rabbit Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of phosphorylated serine 21 of the Peroxisome Proliferator-Activated Receptor Alpha (PPARα). This antibody is produced using high-quality rabbit polyclonal antibodies, ensuring excellent performance and reproducibility.

The Peroxisome Proliferator-Activated Receptor Alpha (PPARα) is a nuclear receptor that plays a crucial role in regulating lipid metabolism and energy homeostasis. Phosphorylation of serine 21 is known to modulate the activity of PPARα, making it an important target for research in various biological processes.

The PPAR ALPHA(PHOSPHO SER21) Rabbit Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It exhibits minimal cross-reactivity with non-phosphorylated PPARα and other related proteins, ensuring accurate and reliable results.

This antibody is supplied as a liquid formulation, ready to use for immediate experimentation. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering. The product is stored at -20°C to maintain its stability and activity.

In summary, the PPAR ALPHA(PHOSPHO SER21) Rabbit Polyclonal Antibody is a valuable tool for researchers studying the phosphorylation status of PPARα. Its high specificity, sensitivity, and ease of use make it an ideal choice for a wide range of applications in the field of lipid metabolism and energy homeostasis research.