PTEN(Phospho Ser385) Polyclonal Antibody

This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway. The use of a non-canonical (CUG) upstream initiation site produces a longer isoform that initiates translation with a leucine, and is thought to be preferentially associated with the mitochondrial inner membrane. This longer isoform may help regulate ener

Introducing the PTEN Phospho-Ser385 Polyclonal Antibody, meticulously developed by BT Lab, a renowned name in the field of life sciences. This cutting-edge antibody is designed to specifically target and detect the phosphorylated form of PTEN at serine 385, enabling researchers to delve deeper into the intricate mechanisms of cellular signaling pathways.

Crafted with utmost precision and utilizing state-of-the-art technology, this antibody exhibits exceptional sensitivity and specificity, ensuring accurate and reliable results. Its high affinity for the phosphorylated PTEN at serine 385 allows for precise identification and quantification, facilitating comprehensive analysis of PTEN-mediated cellular processes.

The PTEN Phospho-Ser385 Polyclonal Antibody is meticulously validated through rigorous quality control measures, guaranteeing optimal performance and reproducibility. Its robust nature ensures consistent results across various experimental conditions, making it an invaluable tool for researchers in diverse scientific disciplines.

With its user-friendly application protocol, this antibody offers ease of use, saving valuable time and effort in the laboratory. Its compatibility with multiple techniques, including Western blotting, immunohistochemistry, and immunofluorescence, provides versatility and flexibility in experimental design.

Furthermore, the PTEN Phospho-Ser385 Polyclonal Antibody is manufactured using premium quality materials, adhering to stringent ethical and regulatory standards. This commitment to excellence ensures the utmost reliability and integrity of the antibody, empowering researchers to advance their scientific endeavors with confidence.

In summary, the PTEN Phospho-Ser385 Polyclonal Antibody by BT Lab is a superior research tool, meticulously designed to enable precise detection and analysis of phosphorylated PTEN at serine 385. With its exceptional sensitivity, specificity, and versatility, this antibody empowers researchers to unravel the complexities of cellular signaling pathways and contribute to groundbreaking discoveries in the field of life sciences.