PTH/PTHrP-R Polyclonal Antibody

The protein encoded by PTH1R (parathyroid hormone 1 receptor) is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for PTH1R.

The PTH/PTHrP-R Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and analysis of parathyroid hormone (PTH) and parathyroid hormone-related protein (PTHrP) receptors. This antibody is produced using advanced techniques to ensure high affinity and specificity, making it an ideal choice for various applications in research and diagnostics.

The PTH/PTHrP-R Polyclonal Antibody exhibits exceptional performance in immunohistochemistry (IHC), immunofluorescence (IF), and western blotting (WB) assays. It recognizes and binds to the PTH/PTHrP receptors with remarkable precision, enabling accurate identification and quantification of these receptors in various biological samples.

This antibody is manufactured using high-quality materials and undergoes rigorous quality control measures to ensure consistent and reliable results. It is validated for use in multiple species, including human, mouse, and rat, allowing for broad applicability across different research models.

The PTH/PTHrP-R Polyclonal Antibody offers researchers and clinicians a valuable tool for investigating the role of PTH and PTHrP receptors in various physiological and pathological processes. Its exceptional sensitivity and specificity make it an indispensable asset in studying bone metabolism, calcium homeostasis, and related disorders.

In summary, the PTH/PTHrP-R Polyclonal Antibody is a highly reliable and versatile reagent that provides accurate and reproducible results in the detection and analysis of PTH and PTHrP receptors. Its exceptional performance and broad applicability make it an essential tool for researchers and clinicians working in the field of endocrinology and related disciplines.