CADM1 Antibody

Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. This gene is also known as IGSF4, SYNCAM or TSLC1, and it is mapped to 11q23.3. It functions as a homophilic cell adhesion molecule at the synapse. Expression of the isolated cytoplasmic tail of CADM1 in neurons inhibited synapse assembly. Conversely, expression of full-length protein in non-neuronal cells induced synapse formation by cocultured hippocampal neurons with normal release properties. It has been shown to interact with EPB41L3.