Synthesized peptide derived from human protein . at AA range: 290-370
Storage:
Rabbit
Storage:
-20°C/1 year
Clonality:
Polyclonal
Isotype:
IgG
Concentration:
1 mg/ml
Observed Band:
46kD
GeneID（Human）:
349667
Human Swiss-Prot No:
Q86UN3
Cellular localization:
Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft . Cell projection, dendrite . Perikaryon . Cell projection, axon . Localized to the surface of neurons, including axons. Detected close to synapses, but is excluded from synapses. .
Background:
function:May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.,PTM:Undergoes zinc metalloproteinase-mediated ectodomain shedding in neuroblastoma cells; where BRE is released as a full-length ectodomain and an N-terminal fragment containing the leucine-rich repeat (LRR) region of the protein.,similarity:Belongs to the Nogo receptor family.,similarity:Contains 8 LRR (leucine-rich) repeats.,subcellular location:Localized to the surface of neurons, including axons.,tissue specificity:Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.,
