Rag B Polyclonal Antibody

Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.

The Rag B Polyclonal Antibody is a highly specific and sensitive antibody designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human Rag B protein. The resulting polyclonal antibody is purified using protein A affinity chromatography to ensure high specificity and purity.

The Rag B Polyclonal Antibody is suitable for use in Western blotting, immunoprecipitation, and immunofluorescence assays. It has been validated for use in human, mouse, and rat samples, making it a versatile tool for researchers in various fields.

This antibody has been shown to recognize endogenous levels of Rag B protein in various cell types and tissues. It has also been demonstrated to be highly specific, showing no cross-reactivity with other related proteins.

The Rag B Polyclonal Antibody is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative. It is available in various sizes to meet the needs of different research applications.

Overall, the Rag B Polyclonal Antibody is a reliable and high-quality tool for researchers studying the role of Rag B protein in various cellular processes. Its high specificity and sensitivity make it an ideal choice for use in a wide range of research applications.