RASA1 Polyclonal Antibody

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expres

The RASA1 Polyclonal Antibody, offered by Dana Biosciences, is a highly specific and sensitive tool for the detection of RASA1 protein in various biological samples. This antibody has been rigorously tested and validated for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence.

The RASA1 protein is a critical regulator of cell signaling pathways, and its dysregulation has been implicated in a variety of diseases, including cancer and cardiovascular disorders. The RASA1 Polyclonal Antibody is designed to recognize and bind to the RASA1 protein with high affinity and specificity, enabling researchers to accurately measure its expression levels and activity in various experimental systems.

This antibody is produced using state-of-the-art techniques and is purified to ensure maximum specificity and sensitivity. It is supplied in a convenient format, with ample quantities for multiple experiments. The RASA1 Polyclonal Antibody is an essential tool for researchers studying the role of RASA1 in various biological processes and diseases, and it is backed by Dana Biosciences' commitment to quality and customer satisfaction.