Recombinant Complement Component 5 (C5)

Prokaryotic expression

Product No.

RPB969Hu01

Organism Species

Homo sapiens (Human).

Source

Prokaryotic expression

Host

E.coli

Endotoxin Level

<1.0EU per 1µg (determined by the LAL method)

Subcellular Location

Secreted

Predicted Molecular Mass

41.7kDa

Accurate Molecular Mass

42kDa(Analysis of differences refer to the manual)

Residues & Tags

Gln19~Ser350 with N-terminal His Tag

Buffer Formulation

PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Traits

Freeze-dried powder

Purity

> 95%

Isoelectric Point

5.0

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

If bio-activity of the protein is needed, please check active protein.

UOM

10µg 50µg 200µg 1mg 5mg

SEQUENCE

 

 

 

USAGE

Reconstitute in ddH₂O to a concentration of 0.1-0.25 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

 

Magazine	Citations
Journal of Clinical Immunology	Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease. PubMed: 22941511
Journal of Neuroimmunology	Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis Pubmed:27235358
Cancer Letters	Complement C5a/C5aR pathway potentiates the pathogenesis Q5 of gastric cancer by down-regulating p21 expression pubmed:29031586
Proteomics Clinical Applications	iTRAQ‐Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism Pubmed:29274201
American journal of physiology. Endocrinology and metabolism	Impaired insulin signaling in the B10.D2-Hc H2 H2-T18/oSnJ mouse model of complement factor 5 (C5) deficiency Pubmed: 31084499
Proteomics Clinical Applications	Comparative proteomics analysis of serum proteins in gestational diabetes during early and middle stages of pregnancy Pubmed: 31162828
Aging	C5aR deficiency attenuates the breast cancer development via the p38/p21 axis Pubmed: 32669478

Catalog No.	Related products for research use of Homo sapiens (Human) Organism species	Applications (RESEARCH USE ONLY!)
RPB969Hu01	Recombinant Complement Component 5 (C5)	Positive Control; Immunogen; SDS-PAGE; WB.
RPB969Hu02	Recombinant Complement Component 5 (C5)	Positive Control; Immunogen; SDS-PAGE; WB.
PAB969Hu01	Polyclonal Antibody to Complement Component 5 (C5)	WB; IHC; ICC; IP.
LAB969Hu71	Biotin-Linked Polyclonal Antibody to Complement Component 5 (C5)	WB; IHC; ICC.
MAB969Hu22	Monoclonal Antibody to Complement Component 5 (C5)	WB; IHC; ICC; IP.
SEB969Hu	ELISA Kit for Complement Component 5 (C5)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMB969Hu	Magnetic Luminex Assay Kit for Complement Component 5 (C5) ,etc.	Magnetic Luminex Assay for Antigen Detection.