Recombinant Cytochrome C Oxidase Subunit II (COX2)

Prokaryotic expression

Product No.

RPD284Ra01

Organism Species

Rattus norvegicus (Rat).

Source

Prokaryotic expression

Host

E.coli

Endotoxin Level

<1.0EU per 1µg (determined by the LAL method)

Subcellular Location

Mitochondrion

Predicted Molecular Mass

20.4kDa

Accurate Molecular Mass

22kDa(Analysis of differences refer to the manual)

Residues & Tags

Ile83~Ile227 with N-terminal His Tag

Buffer Formulation

20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose.

Traits

Freeze-dried powder

Purity

> 90%

Isoelectric Point

4.3

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

If bio-activity of the protein is needed, please check active protein.

UOM

10µg 50µg 200µg 1mg 5mg

SEQUENCE

 

 

 

USAGE

Reconstitute in ddH₂O to a concentration of 0.1-0.25 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

 

Magazine	Citations
Radiation Research	Molecular Mechanisms Underlying Chemopreventive Activities of Glycyrrhizic Acid against UVB- Radiation-Induced Carcinogenesis in SKH-1 Hairless Mouse Epidermis PubMed: 21545294
Photodermatology, Photoimmunology & Photomedicine	Diallyl sulfide protects against ultraviolet B-induced skin cancers in SKH-1 hairless mouse: analysis of early molecular events in carcinogenesis Wiley: source
Journal of Drug Targeting	Discovery of a novel anti-cancer agent targeting both topoisomerase I and II in hepatocellular carcinoma Hep3B cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde. Pubmed:26707867
Drug Des Devel Ther	Discovery of a novel anticancer agent with both anti-topoisomerase I and II activities in hepatocellular carcinoma SK-Hep-1 cells in vitro and in vivo: Cinnamomum verum component 2-methoxycinnamaldehyde Pubmed:26792981
Sci Total Environ.	The effects of particulate matter on inflammation of respiratory system: Differences betweenmale and female. pubmed:28174048
Frontiers in Pharmacology	Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus. pubmed:28553224
Cytokine	Soy isoflavone genistein attenuates lipopolysaccharide-induced cognitive impairments in the rat via exerting anti-oxidative and anti-inflammatory effects pubmed:29102164
Cell Stress & Chaperones	Effect of single and repeated heat stress on chemical signals of heat shock response cascade in the rat's heart. pubmed:29178005
Molecular Carcinogenesis	Quercetin‐3‐methyl ether inhibits esophageal carcinogenesis by targeting the AKT/mTOR/p70S6K and MAPK pathways Pubmed:30035335
Neuroscience	Celecoxib prevents cognitive impairment and neuroinflammation in soluble Amyloid β-treated rats Pubmed:29306052
Inflammopharmacology	Polar extract of protects cartilage homeostasis: possible mechanism of action Pubmed:29313174
Regulatory Toxicology and Pharmacology	Targeted inhibition of tumor survival, metastasis and angiogenesis by Acacia ferruginea mediated regulation of VEGF, inflammatory mediators, cytokine profile and … Pubmed:29678767
Current Nutrition & Food Science	Barrier Strengthening and Anti-inflammatory Effect of Cucurbit Fruits on Intestinal Epithelial Cells In-vitro 10.2174:1573401313666170427123153
Metabolic Brain Disease	Berberine ameliorates lipopolysaccharide-induced learning and memory deficit in the rat: insights into underlying molecular mechanisms Pubmed: 30456649
Metabolic Brain Disease	Trigonelline protects hippocampus against intracerebral Aβ (1–40) as a model of Alzheimer's disease in the rat: insights into underlying mechanisms Pubmed: 30421246
Inflammopharmacology	Chandrasekaran Chinampudur Velusami, Edwin Jothie Richard &
Life Sciences	1, 25-(OH) 2D3 protects Schwann cells against advanced glycation end products-induced apoptosis through PKA-NF-κB pathway Pubmed: 30928409
Biosci Biotechnol Biochem	Polydatin ameliorates chemotherapy-induced cognitive impairment (chemobrain) by inhibiting oxidative stress, inflammatory response, and apoptosis in rats Pubmed: 31992173
Nutrients	Dietary Supplementation of Foxtail Millet Ameliorates Colitis-Associated Colorectal Cancer in Mice via Activation of Gut Receptors and Suppression of the STAT3 … Pubmed: 32784751
Journal of Diabetes Research	Regulation and Mechanism of miR-518d through the PPARα-Mediated NF-κB Pathway in the Development of Gestational Diabetes Mellitus Pubmed: 33123597
Journal of Information and Computational Science	Rewiring of chemically modified MAPK pathway and its downstream targets by rosmarinic acid in mice dermal cancer
	Association between Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2 Levels in Patients with Non-small Cell Carcinoma of Lung
Biotechnol Rep	Targeting NF-¦ÊB mediated cell signaling pathway and inflammatory mediators by 1, 2-diazole in A549 cells in vitro 33598414
Brain Sci	Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial … 34942919

Catalog No.	Related products for research use of Rattus norvegicus (Rat) Organism species	Applications (RESEARCH USE ONLY!)
RPD284Ra01	Recombinant Cytochrome C Oxidase Subunit II (COX2)	Positive Control; Immunogen; SDS-PAGE; WB.
PAD284Ra01	Polyclonal Antibody to Cytochrome C Oxidase Subunit II (COX2)	WB; IHC
SED284Ra	ELISA Kit for Cytochrome C Oxidase Subunit II (COX2)	Enzyme-linked immunosorbent assay for Antigen Detection.
LMD284Ra	Magnetic Luminex Assay Kit for Cytochrome C Oxidase Subunit II (COX2) ,etc.	Magnetic Luminex Assay for Antigen Detection.