Cloud-clone
SKU(재고 관리 코드):RPB050Hu01
Recombinant Estrogen Receptor Alpha (ERa)
Recombinant Estrogen Receptor Alpha (ERa)
Prokaryotic expression
Product No.
RPB050Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane, Nucleus, Cytoplasm
Predicted Molecular Mass
33.4kDa
Accurate Molecular Mass
33kDa(Analysis of differences refer to the manual)
Residues & Tags
Ser178~Met438 with N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
9.0
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| The Journal of Steroid Biochemistry and Molecular Biology | Neuroprotective action of raloxifene against hypoxia-induced damage in mouse hippocampal cells depends on ERα but not ERβ or GPR30 signalling Pubmed:24846829 |
| Biochem Biophys Res Commun | Differential expression of estrogen receptor α and β isoforms in multiple and solitary leiomyomas PubMed: 26529545 |
| Journal of Environmental Sciences | Bisphenol A exposure alters release of immune and developmental modulators and expression of estrogen receptors in human fetal lung fibroblasts science:S1001074216300924 |
| cellular microbiology | Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked. pubmed:28076660 |
| Journal of Steroid Biochemistry and Molecular Biology | Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling pubmed:28263910 |
| Cellular Physiology and Biochemistry | Antiestrogenic Activity of the Xi-Huang Formula for Breast Cancer by Targeting the Estrogen Receptor α Pubmed:29975948 |
| Carleton University Research Virtual Environment | In Vitro Study of Mechanisms Underlying the Developmental Effects of Bisphenol A Using Human Fetal Lung Fibroblasts |
| Clinical Breast Cancer | Vitamin D receptor in breast cancer tissues and its relation to estrogen receptor alpha (ER-a) gene expression and serum 25-hydroxyvitamin D levels in Egyptian Doi: 10.1016/j.clbc.2018.12.019 |
| Journal of geriatric psychiatry and neurology | ERα Gene Promoter Methylation in Cognitive Function and Quality of Life of Patients With Alzheimer Disease Pubmed: 30947592 |
| mBio | The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription … 34488451 |
| Cardiometry | Modifying effect of obesity on the content of sex hormones and their receptors in endometrial adenocarcinoma and its surrounding tissue |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB050Hu02 | Recombinant Estrogen Receptor Alpha (ERa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB050Hu01 | Recombinant Estrogen Receptor Alpha (ERa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB050Hu01 | Polyclonal Antibody to Estrogen Receptor Alpha (ERa) | WB; IHC; ICC; IP. |
| MAB050Hu22 | Monoclonal Antibody to Estrogen Receptor Alpha (ERa) | WB; IHC; ICC; IP. |
| SEB050Hu | ELISA Kit for Estrogen Receptor Alpha (ERa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB050Hu | Magnetic Luminex Assay Kit for Estrogen Receptor Alpha (ERa) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
