SKU(재고 관리 코드):RPB897Hu01
Recombinant Insulin Degrading Enzyme (IDE)
Recombinant Insulin Degrading Enzyme (IDE)
Prokaryotic expression
Product No.
RPB897Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Nucleus, Secreted, Cytoplasm
Predicted Molecular Mass
29.7kDa
Accurate Molecular Mass
30kDa(Analysis of differences refer to the manual)
Residues & Tags
Ala753~Pro973 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
7.2
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Magazine | Citations |
J Neurochem | Reduction PubMed: 26442993 |
African Journal of Pharmacy and Pharmacology | Peptide hydroxamate derivatives as regulators for insulin receptor signaling and its degradation by zinc metalloprotease in diabetic rats article-full-text-pdf |
Biomedicine & Pharmacotherapy | Vitamin D3 intake as regulator of insulin degrading enzyme and insulin receptor phosphorylationin diabetic rats. pubmed:27930980 |
Biological Trace Element Research | Nigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats 10.1007/s12011-017-1167-z |
Neuroscience | The Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A Pubmed:29406271 |
Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
RPB897Hu01 | Recombinant Insulin Degrading Enzyme (IDE) | Positive Control; Immunogen; SDS-PAGE; WB. |
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LMB897Hu | Magnetic Luminex Assay Kit for Insulin Degrading Enzyme (IDE) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
KSB897Hu01 | ELISA Kit DIY Materials for Insulin Degrading Enzyme (IDE) | Main materials for "Do It(ELISA Kit) Yourself" |