SKU(재고 관리 코드):RPB673Hu01
Recombinant Insulin Like Growth Factor Binding Protein 7 (IGFBP7)
Recombinant Insulin Like Growth Factor Binding Protein 7 (IGFBP7)
Prokaryotic expression
Product No.
RPB673Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted
Predicted Molecular Mass
22.7kDa
Accurate Molecular Mass
25kDa(Analysis of differences refer to the manual)
Residues & Tags
Ser24~Leu50+Gly130~Leu282 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
6.1
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Magazine | Citations |
PLoS One | Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells Pubmed:26974954 |
PLOS ONE | Role of IGFBP7 in Diabetic Nephropathy: TGF-β1 Induces IGFBP7 via Smad2/4 in Human Renal Proximal Tubular Epithelial Cells. pubmed:26974954 |
Journal of Alzheimers Disease | Urine-Based Biomarkers for Alzheimer's Disease Identified Through Coupling Computational and Experimental Methods Pubmed:30040720 |
Cancers (Basel). | IGFBP7 Drives Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibition in Lung Cancer Pubmed: 30609749 |
Advances in Medical Sciences | Insulin-like growth factor-binding protein 7 (IGFBP 7) as a new biomarker in coronary heart disease Pubmed: 30769262 |
PLoS One | Altered insulin-like growth factor-2 signaling is associated with psychopathology and cognitive deficits in patients with schizophrenia Pubmed: 32191705 |
Scientific reports | Discovery of novel biomarkers for atherosclerotic aortic aneurysm through proteomics-based assessment of disease progression Pubmed: 32286426 |
Genet Med | SNORD116 and growth hormone therapy impact IGFBP7 in Prader¨CWilli syndrome 34040195 |
Sci Rep | Biomarkers of persistent renal vulnerability after acute kidney injury recovery 34707157 |
Biomolecules | IGFBP7 Concentration May Reflect Subclinical Myocardial Damage and Kidney Function in Patients with Stable Ischemic Heart Disease Pubmed:35204773 |
Biomolecules | Insulin-Like Growth Factor-Binding Protein 7 (IGFBP-7)—New Diagnostic and Prognostic Marker in Symptomatic Peripheral Arterial Disease?—Pilot Study Pubmed:35625639 |