Recombinant Interleukin 31 (IL31)

Prokaryotic expression

Product No.

RPB179Ca01

Organism Species

Canis familiaris; Canine (Dog).

Source

Prokaryotic expression

Host

E.coli

Endotoxin Level

<1.0EU per 1µg (determined by the LAL method)

Subcellular Location

Secreted

Predicted Molecular Mass

18.3kDa

Accurate Molecular Mass

15kDa(Analysis of differences refer to the manual)

Residues & Tags

Gln31~Gln159 with N-terminal His Tag

Buffer Formulation

PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.

Traits

Freeze-dried powder

Purity

> 95%

Isoelectric Point

5.2

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

If bio-activity of the protein is needed, please check active protein.

UOM

10µg 50µg 200µg 1mg 5mg

SEQUENCE

 

 

 

USAGE

Reconstitute in ddH₂O to a concentration of 0.1-0.2 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

 

Magazine	Citations
allergy and clinical immunology	Increased serum levels of Interleukin-31 could modulate inflammatory processes in multiple sclerosis Siaic-Review:Source
BMC Immunol	Increased levels of interleukin 31 (IL-31) in osteoporosis PubMed: 2644965
Sci Rep.	Interleukin-31 expression and relation to disease severity in human asthma pmc:PMC4783779
Exp Dermatol.	Immediate-type allergic and protease-mediated reactions are involved in scratching behaviour induced by topical application of Dermatophagoides farinae extract in NC/Nga mice. pubmed:28191683
Nat Commun.	The transcription factor EPAS1 links DOCK8 deficiency to atopic skin inflammation via IL-31 induction. pubmed:28067314
Experimental Dermatology	Immediate-type allergic and protease-media ted reactions are involved in scratching behavior induced by topical application of Dermatophagoides farinae extract in NC/Nga mice doi:10.1111
	アトピー性皮膚炎の痒みの発症機序に関する研究
Indian Journal of Public Health Research & Development	Determination the Role of Interleukin 31 (IL-31) Levels in Three Real Allergic Diseases (Asthma, Rhinitis, Urticaria)

Catalog No.	Related products for research use of Canis familiaris; Canine (Dog) Organism species	Applications (RESEARCH USE ONLY!)
EPB179Ca62	Eukaryotic Interleukin 31 (IL31)	Positive Control; Immunogen; SDS-PAGE; WB.
RPB179Ca01	Recombinant Interleukin 31 (IL31)	Positive Control; Immunogen; SDS-PAGE; WB.
RAB179Ca81	Recombinant Antibody to Interleukin 31 (IL31)	WB; IF; ICC; IHC; IP; FCM.
SEB179Ca	ELISA Kit for Interleukin 31 (IL31)	Enzyme-linked immunosorbent assay for Antigen Detection.