Cloud-clone
SKU(재고 관리 코드):RPB827Hu01
Recombinant Netrin 1 (Ntn1)
Recombinant Netrin 1 (Ntn1)
Prokaryotic expression
Product No.
RPB827Ra01
Organism Species
Rattus norvegicus (Rat).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Secreted, Extracellular matrix
Predicted Molecular Mass
60.5kDa
Accurate Molecular Mass
58kDa(Analysis of differences refer to the manual)
Residues & Tags
Pro313~Pro565 with N-terminal His and GST Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01%skl, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
8.9
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Transplantation Proceedings | Netrin-1: A Novel Universal Biomarker of Human Kidney Injury PubMed: 20620466 |
| Biomarkers | Plasma netrin-1 is a diagnostic biomarker of human cancers PubMed: PMC3143477 |
| Journal of Maternal-Fetal and Neonatal Medicine | Cord blood netrin-1 and -4 concentrations in term pregnancies with normal, restricted and increased fetal growth Informahealthcare: Source |
| 4 | Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity Pubmed:24584118 |
| J Matern?Fetal?Neonatal Med.? | Cord blood netrin-1 and-4 concentrations in term pregnancies with normal, restricted and increased fetal growth Pubmed:24716747 |
| Renal failure. | Urinary netrin-1 and KIM-1 as early biomarkers for septic acute kidney injury Pubmed:25154466 |
| Stem Cell Research & Therapy | Netrin-1 acts as a non-canonical angiogenic factor produced by human Wharton’s jelly mesenchymal stem cells (WJ-MSC) articles:10.1186 |
| Oncotarget | The effect of aspirin on circulating netrin-1 levels in humans is dependent on the inflammatory status of the vascular endothelium. pubmed:29156815 |
| Frontiers in Cellular Neuroscience | Neuroprotection Exerted by Netrin-1 and Kinesin Motor KIF1A in Secondary Brain Injury following Experimental Intracerebral Hemorrhage in Rats Pubmed:29375318 |
| Scientific Reports | Netrin-1 promotes diabetic corneal wound healing through molecular mechanisms mediated via the adenosine 2B receptor Pubmed:29662125 |
| Family Practice and Palliative Care | Relationship of serum netrin-1 levels with breast masses Doi: 10.22391/fppc.467700 |
| JOURNAL OF BIOLOGICAL CHEMISTRY | Role of microRNA in CB1 antagonist-mediated regulation of adipose tissue macrophage polarization and chemotaxis during diet-induced obesity Pubmed: 30910812 |
| International Journal of Molecular Sciences | Downregulation of the Netrin-1 Receptor UNC5b Underlies Increased Placental Angiogenesis in Human Gestational Diabetes Mellitus Pubmed: 30897795 |
| Cancer Biomark | Serum netrin-1 as a biomarker for colorectal cancer detection Pubmed: 32474463 |
| Níveis Elevados de Netrina-1 e IL-1β em Mulheres Idosas com SCA: Pior Prognóstico no Acompanhamento de Dois Anos | |
| Tuberk Toraks | Association of plasma netrin-1 level with inflammatory balance and comorbidities in patients with acute exacerbation of COPD 33853303 |
| Adv Healthc Mater | Conductive Hydrogel Conduits with Growth Factor Gradients for Peripheral Nerve Repair in Diabetics with Non‐suture Tape Pubmed:35670309 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB827Hu01 | Recombinant Netrin 1 (Ntn1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB827Hu01 | Polyclonal Antibody to Netrin 1 (Ntn1) | WB; IHC; ICC; IP. |
| MAB827Hu22 | Monoclonal Antibody to Netrin 1 (Ntn1) | WB; IHC; ICC; IP. |
| SEB827Hu | ELISA Kit for Netrin 1 (Ntn1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB827Hu | Magnetic Luminex Assay Kit for Netrin 1 (Ntn1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
