SKU(재고 관리 코드):RPB824Hu01
Recombinant Nuclear Factor Kappa B (NFkB)
Recombinant Nuclear Factor Kappa B (NFkB)
Prokaryotic expression
Product No.
RPB824Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1μg
Subcellular Location
Nucleus, Cytoplasm
Predicted Molecular Mass
40.6kDa
Accurate Molecular Mass
39kDa(Analysis of differences refer to the manual)
Residues & Tags
Pro42~Met367 with N-terminal His Tag
Buffer Formulation
20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
8.8
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Magazine | Citations |
Reproductice Science | Surgical Removal of Endometrioma Decreases the NF-kB1 (p50/105) and NF-kB p65 (Rel A) Expression in the Eutopic Endometrium During the Implantation Window Sagepub: Source |
International Immunopharmacology | Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis PubMed: 21642017 |
PLoS One | New Method to Isolate and Culture Rat Kupffer Cells PubMed: PMC3743898 |
World Journal of Gastroenterology | Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats PubMed: PMC3660814 |
Experimental and Therapeutic Medicine | Shuangtengbitong tincture treatment of collagen-induced arthritis via downregulation of the expression of IL-6, IL-8, TNF-α and NF-κB PubMed: PMC3570159 |
PLoS One. | Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion Pubmed:24816434 |
Free Radical Biology and Medicine | Involvement of nitric oxide with activation of Toll-like receptor 4 signaling in mice with dextran sodium sulfate-induced colitis Pubmed:24992835 |
BBA Clin | Long-term warfarin therapy and biomarkers for osteoporosis and atherosclerosis PubMed: 26674156 |
J Clin Diagn Res | Serological Analysis of Alpha-synuclein and NF-κB in Parkinson’s Disease Patients PubMed: 26155470 |
Eur J Obstet Gynecol Reprod Biol | Hysteroscopic polypectomy decreases NF-κB1 expression in the mid-secretory endometrium of women with endometrial polyp PubMed: 25898371 |
Asian Pacific Journal of Cancer Prevention | Plasma nuclear factor kappa B and serum peroxiredoxin 3 in early diagnosis of hepatocellular carcinoma. PubMed: 25743848 |
Acta Biochim Pol | Preventive use of Lactobacillus plantarum LS/07 and inulin to relieve symptoms of acute colitis. PubMed: 26345092 |
Acta Veterinaria | Use Of The Prebiotic Inulin In The Prevention Of Adverse Signs Of Acute Colitis View: J |
Neurochem Res | Protective Effect of Oral Hesperetin Against Unilateral Striatal 6-Hydroxydopamine Damage in the Rat PubMed: 26700436 |
Transplant Proc | L-Alanyl-Glutamine Attenuates Oxidative Stress in Liver Transplantation Patients PubMed: 26518955 |
Journal of Food Science | Effects of Hyriopsis cumingii Polysaccharides on Mice Immunologic Receptor, Transcription Factor, and Cytokine Pubmed:27061742 |
IJBPAS | THE PROPHYLACTIC EFFICIENCY OF LYCOPENE AGAINST GAMMA IRRADAITION-INDIUCED CARDIAC OXIDATIVE DAMAGE, PATHOLOGY AND APOPTOSIS IN RATS publication:298838934 |
Basic & Clinical Pharmacology & Toxicology | Placental Growth Factor Triggers Epithelial-to-Mesenchymal Transition-like Changes in Rat Type II Alveolar Epithelial Cells: Activation of Nuclear Factor κB Signalling Pathway doi:10.1111 |
Peptides. | Carnosine ameliorates cognitive deficits in streptozotocin-induced diabetic rats: Possible involved mechanisms. pubmed:27777064 |
british journal of pharmacology | Forskolin, a hedgehog signalling inhibitor, attenuates carbon tetrachloride-induced liver fibrosis in rats. pubmed:27590029 |
european journal of pharmacology | Garlic active constituent s-allyl cysteine protects against lipopolysaccharide-induced cognitive deficits in the rat: Possible involved mechanisms. pubmed:27915041 |
european journal of pharmacology | S-allyl cysteine ameliorates cognitive deficits in streptozotocin-diabetic rats via suppression of oxidative stress, inflammation, and acetylcholinesterase. pubmed:27887948 |
Psychopharmacology (Berl) | Ellagic acid ameliorates learning and memory deficits in a rat model of Alzheimer's disease: an exploration of underlying mechanisms. pubmed:28303372 |
biomedicine & pharmacotherapy | Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat. pubmed:28199883 |
biomedicine & pharmacotherapy | Diosgenin ameliorates development of neuropathic pain in diabetic rats: Involvement of oxidative stress and inflammation. pubmed:28033582 |
Toxicology and Applied Pharmacology | Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) pubmed:28974454 |
Microbial Immunology | Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota pubmed:28713364 |
Journal of Biomechanics | The shear wave elastic modulus and the increased nuclear factor kappa B(NF-kB/p65) and cyclooxygenase-2 (COX-2) expression in the area of myofascial trigger points activated in a rat model by blunt trauma to the vastus medialis pubmed:29137729 |
European Journal of Pharmacology | In vivo cellular and molecular gastroprotective mechanisms of chrysin; Emphasis on oxidative stress, inflammation and angiogenesis pubmed:29126792 |
Frontiers in Pharmacology | Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus. pubmed:28553224 |
International Journal of Medicinal Mushrooms | Anti-Inflammatory Activity and Bioactive Constituents of Cultivated Fruiting Bodies of Xylaria nigripes (Ascomycetes), a Chinese Medicinal Fungus. pubmed:29256845 |
Biomedicine & pharmacotherapy | Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms pubmed:28061403 |
International Immunopharmacology | Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms. pubmed:29190543 |
Food and Chemical Toxicology | Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin–induced diabetic rats Pubmed:30026088 |
Neurotoxicity Research | Protective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta-Induced Toxicity in SH-SY5Y Cells Pubmed:29869772 |
European Journal of Pharmacology | Naringenin ameliorates learning and memory impairment following systemic lipopolysaccharide challenge in the rat Pubmed:29518393 |
Experimental biology and medicine (Maywood) | Shock waves increase pulmonary vascular leakage, inflammation, oxidative stress, and apoptosis in a mouse model Pubmed:29984607 |
Acta Veterinaria Belgrade | Anti-inflammatory potential of Lactobacillus plantarum LS/07 in acute colitis in rats 10.2478:acve-2018-0005 |
Taiwanese Journal of Obstetrics & Gynecology | HMGB1-RAGE signaling pathway in pPROM Pubmed:29673663 |
Acta Veterinaria Brno | Improvement of colitis by LS/07 and inulin 10.2754:avb201786040399 |
Drug Discoveries & Therapeutics | The potential antifibrotic impact of apocynin and alpha-lipoic acid in concanavalin A-induced liver fibrosis in rats: Role of NADPH oxidases 1 and 4 Pubmed:29760339 |
Life Sciences | Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin-induced diabetic rats Pubmed: 30205096 |
Life Sciences | Sitagliptin attenuates intestinal ischemia/reperfusion injury via cAMP/PKA, PI3K/Akt pathway in a glucagon-like peptide 1 receptor-dependent manner Pubmed: 30195035 |
Journal of Traditional Chinese Medical Sciences | Effect of Dachaihu Decoction on non-alcoholic fatty liver disease model rats induced by a high-fat high-sugar diet |
Naunyn-Schmiedeberg's archives of pharmacology | Amitriptyline attenuates bleomycin-induced pulmonary fibrosis: modulation of the expression of NF-κβ, iNOS, and Nrf2 Pubmed: 30474696 |
Archives of Physiology and Biochemistry | Diabetes-induced testicular oxidative stress, inflammation, and caspase-dependent apoptosis: the protective role of metformin Pubmed: 30513216 |
Journal of Functional Foods | Complex interaction of dietary fat and Alaskan bog blueberry supplementation influences manganese mediated neurotoxicity and behavioral impairments |
Scientific Reports | Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis Pubmed: 30651572 |
Journal of Pain Researc | Increased cerebral nuclear factor kappa B in a complex regional pain syndrome rat model: possible relationship between peripheral injury and the brain Pubmed: 30881100 |
Antioxidants | Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin–Induced Diabetic Rats: Combined Protective Effects of Malaysian … Pubmed: 31600920 |
journal of biochemical and molecular toxicology | Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells Pubmed: 31916655 |
Life Sci | New insights into the protection of growth hormone in cisplatin-induced nephrotoxicity: The impact of IGF-1 on the Keap1-Nrf2/HO-1 signaling Pubmed: 32209424 |
European Review for Medical and Pharmacological Sciences | Effects of lncRNA gm4419 on rats with hypertensive cerebral atherosclerosis through NF-κB pathway Pubmed: 31858567 |
J Ethnopharmacol | Effects of fermented ginseng on the gut microbiota and immunity of rats with antibiotic-associated diarrhea Pubmed: 33217518 |
Odontology | Effects of different pulp-capping materials on cell death signaling pathways of lipoteichoic acid-stimulated human dental pulp stem cells Pubmed: 33206337 |
LIFE SCIENCES | Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and … Pubmed: 33148421 |
JOURNAL OF ETHNOPHARMACOLOGY | Morroniside attenuates apoptosis and pyroptosis of chondrocytes and ameliorates osteoarthritic development by inhibiting NF-κB signaling Pubmed: 33022338 |
Journal of Cosmetic Dermatology | Examination of androgenetic alopecia with serum biomarkers Pubmed: 32969583 |
NEUROPSYCHOBIOLOGY | Diosgenin Attenuates Cognitive Impairment in Streptozotocin-Induced Diabetic Rats: Underlying Mechanisms Pubmed: 32526752 |
journal of ethnopharmacology | UPLC-Orbitrap HRMS metabolic profiling of Cymbopogon citratus cultivated in Egypt; neuroprotective effect against AlCl3-induced neurotoxicity in rats Pubmed: 32376365 |
BIOMEDICINE & PHARMACOTHERAPY | Protective effects of bee bread on testicular oxidative stress, NF-κB-mediated inflammation, apoptosis and lactate transport decline in obese male rats Pubmed: 33152939 |
Journal of Diabetes Research | Regulation and Mechanism of miR-518d through the PPARα-Mediated NF-κB Pathway in the Development of Gestational Diabetes Mellitus Pubmed: 33123597 |
Folia Biologica | Effect of Graviola (Annona Muricata l.) and Ginger (Zingiber Officinale Roscoe) on Diabetes Mellitus Induced in Male Wistar Albino Rats |
TOXICOLOGY IN VITRO | Cyproheptadine causes apoptosis and decreases inflammation by disrupting thiol/disulfide balance and enhancing the levels of SIRT1 in C6 glioblastoma cells 33675893 |
Hum Exp Toxicol | Alamandine significantly reduces doxorubicin-induced cardiotoxicity in rats 33882726 |
J Food Biochem | Masseter muscle and gingival tissue inflammatory response following treatment with high©\fructose corn syrup in rats: Anti©\inflammatory and antioxidant effects of kefir 33864286 |
Open Access Macedonian Journal of Medical Sciences | The Potential of Nano Curcumin in Preventing the Formation of Artificial Antisperm Antibody in Wistar Rats through Inflammatory Pathway Regulation |
Eur Rev Med Pharmacol Sci | Vitamin D supplementation inhibits NF-kß signaling pathway in lean and obese women with PCOS Pubmed:35731068 |
BMC Nephrol | Effect of subacute poisoning with lambdacyhalothrin on vascular endothelial growth factor 2 receptor in mice kidneys Pubmed:35643467 |
Antioxidants | Therapeutic Effects of Bee Bread on Obesity-Induced Testicular-Derived Oxidative Stress, Inflammation, and Apoptosis in High-Fat Diet Obese Rat Model … Pubmed:35204140 |
Journal of Pharmaceutical Research International | Concomitant Administration of Rosuvastatin and Lefleunamide in Low doses Synergize Against Complete Freund's Adjuvant (CFA)-Induced Rheumatoid … |
Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
RPB824Hu01 | Recombinant Nuclear Factor Kappa B (NFkB) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB824Hu03 | Recombinant Nuclear Factor Kappa B (NFkB) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB824Hu02 | Recombinant Nuclear Factor Kappa B (NFkB) | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB824Hu01 | Polyclonal Antibody to Nuclear Factor Kappa B (NFkB) | WB; IHC; ICC; IP. |
PAB824Hu02 | Polyclonal Antibody to Nuclear Factor Kappa B (NFkB) | WB; IHC; ICC; IP. |
LAB824Hu81 | FITC-Linked Polyclonal Antibody to Nuclear Factor Kappa B (NFkB) | WB; IHC; ICC; IF. |
LAB824Hu71 | Biotin-Linked Polyclonal Antibody to Nuclear Factor Kappa B (NFkB) | WB; IHC; ICC. |
MAB824Hu22 | Monoclonal Antibody to Nuclear Factor Kappa B (NFkB) | WB; IHC; ICC; IP. |
SEB824Hu | ELISA Kit for Nuclear Factor Kappa B (NFkB) | Enzyme-linked immunosorbent assay for Antigen Detection. |
MEB824Hu | Mini Samples ELISA Kit for Nuclear Factor Kappa B (NFkB) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMB824Hu | Magnetic Luminex Assay Kit for Nuclear Factor Kappa B (NFkB) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
KSB824Hu01 | ELISA Kit DIY Materials for Nuclear Factor Kappa B (NFkB) | Main materials for "Do It (ELISA Kit) Yourself". |