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SKU(재고 관리 코드):RPB824Hu01

Recombinant Nuclear Factor Kappa B (NFkB)

Recombinant Nuclear Factor Kappa B (NFkB)

UOM
Purity
Organism species

Prokaryotic expression

Product No.

RPB824Hu01

Organism Species

Homo sapiens (Human).

Source

Prokaryotic expression

Host

E.coli

Endotoxin Level

<1.0EU per 1μg

Subcellular Location

Nucleus, Cytoplasm

Predicted Molecular Mass

40.6kDa

Accurate Molecular Mass

39kDa(Analysis of differences refer to the manual)

Residues & Tags

Pro42~Met367 with N-terminal His Tag

Buffer Formulation

20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.

Traits

Freeze-dried powder

Purity

> 90%

Isoelectric Point

8.8

Applications

Positive Control; Immunogen; SDS-PAGE; WB.

If bio-activity of the protein is needed, please check active protein.

UOM

10µg 50µg 200µg 1mg 5mg

 

SEQUENCE

 

 

 

USAGE

Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

STORAGE

Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.

STABILITY

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Magazine Citations
Reproductice Science Surgical Removal of Endometrioma Decreases the NF-kB1 (p50/105) and NF-kB p65 (Rel A) Expression in the Eutopic Endometrium During the Implantation Window Sagepub: Source
International Immunopharmacology Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis PubMed: 21642017
PLoS One New Method to Isolate and Culture Rat Kupffer Cells PubMed: PMC3743898
World Journal of Gastroenterology Long-term aspirin pretreatment in the prevention of cerulein-induced acute pancreatitis in rats PubMed: PMC3660814
Experimental and Therapeutic Medicine Shuangtengbitong tincture treatment of collagen-induced arthritis via downregulation of the expression of IL-6, IL-8, TNF-α and NF-κB PubMed: PMC3570159
PLoS One. Cilostazol Renoprotective Effect: Modulation of PPAR-γ, NGAL, KIM-1 and IL-18 Underlies Its Novel Effect in a Model of Ischemia-Reperfusion Pubmed:24816434
Free Radical Biology and Medicine Involvement of nitric oxide with activation of Toll-like receptor 4 signaling in mice with dextran sodium sulfate-induced colitis Pubmed:24992835
BBA Clin Long-term warfarin therapy and biomarkers for osteoporosis and atherosclerosis PubMed: 26674156
J Clin Diagn Res Serological Analysis of Alpha-synuclein and NF-κB in Parkinson’s Disease Patients PubMed: 26155470
Eur J Obstet Gynecol Reprod Biol Hysteroscopic polypectomy decreases NF-κB1 expression in the mid-secretory endometrium of women with endometrial polyp PubMed: 25898371
Asian Pacific Journal of Cancer Prevention Plasma nuclear factor kappa B and serum peroxiredoxin 3 in early diagnosis of hepatocellular carcinoma. PubMed: 25743848
Acta Biochim Pol Preventive use of Lactobacillus plantarum LS/07 and inulin to relieve symptoms of acute colitis. PubMed: 26345092
Acta Veterinaria Use Of The Prebiotic Inulin In The Prevention Of Adverse Signs Of Acute Colitis View: J
Neurochem Res Protective Effect of Oral Hesperetin Against Unilateral Striatal 6-Hydroxydopamine Damage in the Rat PubMed: 26700436
Transplant Proc L-Alanyl-Glutamine Attenuates Oxidative Stress in Liver Transplantation Patients PubMed: 26518955
Journal of Food Science  Effects of Hyriopsis cumingii Polysaccharides on Mice Immunologic Receptor, Transcription Factor, and Cytokine Pubmed:27061742
IJBPAS THE PROPHYLACTIC EFFICIENCY OF LYCOPENE AGAINST GAMMA IRRADAITION-INDIUCED CARDIAC OXIDATIVE DAMAGE, PATHOLOGY AND APOPTOSIS IN RATS publication:298838934
Basic & Clinical Pharmacology & Toxicology Placental Growth Factor Triggers Epithelial-to-Mesenchymal Transition-like Changes in Rat Type II Alveolar Epithelial Cells: Activation of Nuclear Factor κB Signalling Pathway doi:10.1111
Peptides. Carnosine ameliorates cognitive deficits in streptozotocin-induced diabetic rats: Possible involved mechanisms. pubmed:27777064
british journal of pharmacology Forskolin, a hedgehog signalling inhibitor, attenuates carbon tetrachloride-induced liver fibrosis in rats. pubmed:27590029
european journal of pharmacology Garlic active constituent s-allyl cysteine protects against lipopolysaccharide-induced cognitive deficits in the rat: Possible involved mechanisms. pubmed:27915041
european journal of pharmacology S-allyl cysteine ameliorates cognitive deficits in streptozotocin-diabetic rats via suppression of oxidative stress, inflammation, and acetylcholinesterase. pubmed:27887948
Psychopharmacology (Berl) Ellagic acid ameliorates learning and memory deficits in a rat model of Alzheimer's disease: an exploration of underlying mechanisms. pubmed:28303372
biomedicine & pharmacotherapy Acetyl-l-carnitine protects dopaminergic nigrostriatal pathway in 6-hydroxydopamine-induced model of Parkinson's disease in the rat. pubmed:28199883
biomedicine & pharmacotherapy Diosgenin ameliorates development of neuropathic pain in diabetic rats: Involvement of oxidative stress and inflammation. pubmed:28033582
Toxicology and Applied Pharmacology Sildenafil protects against bile duct ligation induced hepaticfibrosis in rats: Potential role for silent information regulator 1 (SIRT1) pubmed:28974454
Microbial Immunology Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota pubmed:28713364
Journal of Biomechanics The shear wave elastic modulus and the increased nuclear factor kappa B(NF-kB/p65) and cyclooxygenase-2 (COX-2) expression in the area of myofascial trigger points activated in a rat model by blunt trauma to the vastus medialis pubmed:29137729
European Journal of Pharmacology In vivo cellular and molecular gastroprotective mechanisms of chrysin; Emphasis on oxidative stress, inflammation and angiogenesis pubmed:29126792
Frontiers in Pharmacology Docking Studies and Biological Evaluation of a Potential β-Secretase Inhibitor of 3-Hydroxyhericenone F from Hericium erinaceus. pubmed:28553224
International Journal of Medicinal Mushrooms Anti-Inflammatory Activity and Bioactive Constituents of Cultivated Fruiting Bodies of Xylaria nigripes (Ascomycetes), a Chinese Medicinal Fungus. pubmed:29256845
Biomedicine & pharmacotherapy Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms pubmed:28061403
International Immunopharmacology Scutellarin alleviates lipopolysaccharide-induced cognitive deficits in the rat: Insights into underlying mechanisms. pubmed:29190543
Food and Chemical Toxicology Antioxidant, anti-inflammatory and synergistic anti-hyperglycemic effects of Malaysian propolis and metformin in streptozotocin–induced diabetic rats Pubmed:30026088
Neurotoxicity Research Protective Effects of Fibroblast Growth Factor 21 Against Amyloid-Beta-Induced Toxicity in SH-SY5Y Cells Pubmed:29869772
European Journal of Pharmacology  Naringenin ameliorates learning and memory impairment following systemic lipopolysaccharide challenge in the rat Pubmed:29518393
Experimental biology and medicine (Maywood) Shock waves increase pulmonary vascular leakage, inflammation, oxidative stress, and apoptosis in a mouse model Pubmed:29984607
Acta Veterinaria Belgrade Anti-inflammatory potential of Lactobacillus plantarum LS/07 in acute colitis in rats 10.2478:acve-2018-0005
Taiwanese Journal of Obstetrics & Gynecology HMGB1-RAGE signaling pathway in pPROM Pubmed:29673663
Acta Veterinaria Brno Improvement of colitis by LS/07 and inulin 10.2754:avb201786040399
Drug Discoveries & Therapeutics The potential antifibrotic impact of apocynin and alpha-lipoic acid in concanavalin A-induced liver fibrosis in rats: Role of NADPH oxidases 1 and 4 Pubmed:29760339
Life Sciences Malaysian propolis, metformin and their combination, exert hepatoprotective effect in streptozotocin-induced diabetic rats Pubmed: 30205096
Life Sciences Sitagliptin attenuates intestinal ischemia/reperfusion injury via cAMP/PKA, PI3K/Akt pathway in a glucagon-like peptide 1 receptor-dependent manner Pubmed: 30195035
Journal of Traditional Chinese Medical Sciences Effect of Dachaihu Decoction on non-alcoholic fatty liver disease model rats induced by a high-fat high-sugar diet
Naunyn-Schmiedeberg's archives of pharmacology Amitriptyline attenuates bleomycin-induced pulmonary fibrosis: modulation of the expression of NF-κβ, iNOS, and Nrf2 Pubmed: 30474696
Archives of Physiology and Biochemistry Diabetes-induced testicular oxidative stress, inflammation, and caspase-dependent apoptosis: the protective role of metformin Pubmed: 30513216
Journal of Functional Foods Complex interaction of dietary fat and Alaskan bog blueberry supplementation influences manganese mediated neurotoxicity and behavioral impairments
Scientific Reports Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis Pubmed: 30651572
Journal of Pain Researc Increased cerebral nuclear factor kappa B in a complex regional pain syndrome rat model: possible relationship between peripheral injury and the brain Pubmed: 30881100
Antioxidants Oxidative Stress, NF-κB-Mediated Inflammation and Apoptosis in the Testes of Streptozotocin–Induced Diabetic Rats: Combined Protective Effects of Malaysian … Pubmed: 31600920
journal of biochemical and molecular toxicology Indomethacin and juglone inhibit inflammatory molecules to induce apoptosis in colon cancer cells Pubmed: 31916655
Life Sci New insights into the protection of growth hormone in cisplatin-induced nephrotoxicity: The impact of IGF-1 on the Keap1-Nrf2/HO-1 signaling Pubmed: 32209424
European Review for Medical and Pharmacological Sciences Effects of lncRNA gm4419 on rats with hypertensive cerebral atherosclerosis through NF-κB pathway Pubmed: 31858567
J Ethnopharmacol Effects of fermented ginseng on the gut microbiota and immunity of rats with antibiotic-associated diarrhea Pubmed: 33217518
Odontology Effects of different pulp-capping materials on cell death signaling pathways of lipoteichoic acid-stimulated human dental pulp stem cells Pubmed: 33206337
LIFE SCIENCES Effects of combined treatment with Indomethacin and Juglone on AOM/DSS induced colon carcinogenesis in Balb/c mice: Roles of inflammation and … Pubmed: 33148421
JOURNAL OF ETHNOPHARMACOLOGY Morroniside attenuates apoptosis and pyroptosis of chondrocytes and ameliorates osteoarthritic development by inhibiting NF-κB signaling Pubmed: 33022338
Journal of Cosmetic Dermatology Examination of androgenetic alopecia with serum biomarkers Pubmed: 32969583
NEUROPSYCHOBIOLOGY Diosgenin Attenuates Cognitive Impairment in Streptozotocin-Induced Diabetic Rats: Underlying Mechanisms Pubmed: 32526752
journal of ethnopharmacology UPLC-Orbitrap HRMS metabolic profiling of Cymbopogon citratus cultivated in Egypt; neuroprotective effect against AlCl3-induced neurotoxicity in rats Pubmed: 32376365
BIOMEDICINE & PHARMACOTHERAPY Protective effects of bee bread on testicular oxidative stress, NF-κB-mediated inflammation, apoptosis and lactate transport decline in obese male rats Pubmed: 33152939
Journal of Diabetes Research Regulation and Mechanism of miR-518d through the PPARα-Mediated NF-κB Pathway in the Development of Gestational Diabetes Mellitus Pubmed: 33123597
Folia Biologica Effect of Graviola (Annona Muricata l.) and Ginger (Zingiber Officinale Roscoe) on Diabetes Mellitus Induced in Male Wistar Albino Rats
TOXICOLOGY IN VITRO Cyproheptadine causes apoptosis and decreases inflammation by disrupting thiol/disulfide balance and enhancing the levels of SIRT1 in C6 glioblastoma cells 33675893
Hum Exp Toxicol Alamandine significantly reduces doxorubicin-induced cardiotoxicity in rats 33882726
J Food Biochem Masseter muscle and gingival tissue inflammatory response following treatment with high©\fructose corn syrup in rats: Anti©\inflammatory and antioxidant effects of kefir 33864286
Open Access Macedonian Journal of Medical Sciences The Potential of Nano Curcumin in Preventing the Formation of Artificial Antisperm Antibody in Wistar Rats through Inflammatory Pathway Regulation
Eur Rev Med Pharmacol Sci Vitamin D supplementation inhibits NF-kß signaling pathway in lean and obese women with PCOS Pubmed:35731068
BMC Nephrol Effect of subacute poisoning with lambdacyhalothrin on vascular endothelial growth factor 2 receptor in mice kidneys Pubmed:35643467
Antioxidants Therapeutic Effects of Bee Bread on Obesity-Induced Testicular-Derived Oxidative Stress, Inflammation, and Apoptosis in High-Fat Diet Obese Rat Model … Pubmed:35204140
Journal of Pharmaceutical Research International Concomitant Administration of Rosuvastatin and Lefleunamide in Low doses Synergize Against Complete Freund's Adjuvant (CFA)-Induced Rheumatoid …
Catalog No. Related products for research use of Homo sapiens (Human) Organism species Applications (RESEARCH USE ONLY!)
RPB824Hu01 Recombinant Nuclear Factor Kappa B (NFkB) Positive Control; Immunogen; SDS-PAGE; WB.
RPB824Hu03 Recombinant Nuclear Factor Kappa B (NFkB) Positive Control; Immunogen; SDS-PAGE; WB.
RPB824Hu02 Recombinant Nuclear Factor Kappa B (NFkB) Positive Control; Immunogen; SDS-PAGE; WB.
PAB824Hu01 Polyclonal Antibody to Nuclear Factor Kappa B (NFkB) WB; IHC; ICC; IP.
PAB824Hu02 Polyclonal Antibody to Nuclear Factor Kappa B (NFkB) WB; IHC; ICC; IP.
LAB824Hu81 FITC-Linked Polyclonal Antibody to Nuclear Factor Kappa B (NFkB) WB; IHC; ICC; IF.
LAB824Hu71 Biotin-Linked Polyclonal Antibody to Nuclear Factor Kappa B (NFkB) WB; IHC; ICC.
MAB824Hu22 Monoclonal Antibody to Nuclear Factor Kappa B (NFkB) WB; IHC; ICC; IP.
SEB824Hu ELISA Kit for Nuclear Factor Kappa B (NFkB) Enzyme-linked immunosorbent assay for Antigen Detection.
MEB824Hu Mini Samples ELISA Kit for Nuclear Factor Kappa B (NFkB) Enzyme-linked immunosorbent assay for Antigen Detection.
LMB824Hu Magnetic Luminex Assay Kit for Nuclear Factor Kappa B (NFkB) ,etc. Magnetic Luminex Assay for Antigen Detection.
KSB824Hu01 ELISA Kit DIY Materials for Nuclear Factor Kappa B (NFkB) Main materials for "Do It (ELISA Kit) Yourself".
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