Cloud-clone
SKU(재고 관리 코드):RPB317Mu02
Recombinant Perforin 1 (PRF1)
Recombinant Perforin 1 (PRF1)
Prokaryotic expression
Product No.
RPB317Mu02
Organism Species
Mus musculus (Mouse).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane, Secreted, Cytoplasm, Endoplasmic reticulum lumen
Predicted Molecular Mass
39.0kDa
Accurate Molecular Mass
42kDa(Analysis of differences refer to the manual)
Residues & Tags
Val40~Lys355 with N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 90%
Isoelectric Point
8.3
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| Diagnostic Microbiology and Infectious Disease | Granzyme B as a diagnostic marker of tuberculosis in patients with and without HIV coinfection Pubmed:26915636 |
| FASEB JOURNAL | The immunoregulatory effects of CD8 T-cell–derived perforin on diet-induced nonalcoholic steatohepatitis Pubmed: 30951375 |
| Theranostics | A novel Granzyme B nanoparticle delivery system simulates immune cell functions for suppression of solid tumors Pubmed: 31695790 |
| Mol Immunol | CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection Pubmed: 33223223 |
| INVESTIGATIONAL NEW DRUGS | Dual-function chimeric antigen receptor T cells targeting c-Met and PD-1 exhibit potent anti-tumor efficacy in solid tumors Pubmed: 32772342 |
| Am J Transl Res | Combined treatment with epigenetic agents enhances anti-tumor activity of T cells by upregulating the ACRBP expression in hepatocellular carcinoma 34377237 |
| Nat Biomed Eng | Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy 34873307 |
| J Exp Med | Single-cell immune profiling reveals functional diversity of T cells in tuberculous pleural effusion Pubmed:35061012 |
| Catalog No. | Related products for research use of Mus musculus (Mouse) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB317Mu01 | Recombinant Perforin 1 (PRF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB317Mu02 | Recombinant Perforin 1 (PRF1) | Positive Control; Immunogen; SDS-PAGE; WB. |
| APB317Mu01 | Active Perforin 1 (PRF1) | Cell culture; Activity Assays. |
| APB317Mu02 | Active Perforin 1 (PRF1) | Cell culture; Activity Assays. |
| PAB317Mu01 | Polyclonal Antibody to Perforin 1 (PRF1) | WB; IHC; ICC; IP. |
| PAB317Mu02 | Polyclonal Antibody to Perforin 1 (PRF1) | WB; IHC; ICC; IP. |
| LAB317Mu81 | FITC-Linked Polyclonal Antibody to Perforin 1 (PRF1) | WB; IHC; ICC; IF. |
| LAB317Mu71 | Biotin-Linked Polyclonal Antibody to Perforin 1 (PRF1) | WB; IHC; ICC. |
| WEB317Mu | Wide-range ELISA Kit for Perforin 1 (PRF1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEB317Mu | ELISA Kit for Perforin 1 (PRF1) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB317Mu | Magnetic Luminex Assay Kit for Perforin 1 (PRF1) ,etc. | Magnetic Luminex Assay for Antigen Detection. |
