Cloud-clone
SKU(재고 관리 코드):RPB222Hu01
Recombinant Synuclein Alpha (SNCa)
Recombinant Synuclein Alpha (SNCa)
Prokaryotic expression
Product No.
RPB222Hu01
Organism Species
Homo sapiens (Human).
Source
Prokaryotic expression
Host
E.coli
Endotoxin Level
<1.0EU per 1µg (determined by the LAL method)
Subcellular Location
Membrane, Nucleus, Cytoplasm
Predicted Molecular Mass
18.2kDa
Accurate Molecular Mass
21kDa(Analysis of differences refer to the manual)
Residues & Tags
Met1~Ala140 with N-terminal His Tag
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
Traits
Freeze-dried powder
Purity
> 95%
Isoelectric Point
4.5
Applications
Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
UOM
10µg 50µg 200µg 1mg 5mg
SEQUENCE
USAGE
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
STORAGE
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
STABILITY
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
| Magazine | Citations |
| The Journal of Clinical Investigation | Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration PubMed: PMC3428100 |
| Neurobiology of Disease | Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission PubMed: PMC3107939 |
| Nature Communications | Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus PubMed: PMC3265381 |
| Provisional chapter | Mutations of PARK Genes and Alpha-Synuclein and Parkin Concentrations in Parkinson’s Disease Intechopen:Source |
| Nerodegeneration | Apolipoprotein Eε4: A Biomarker for Executive Dysfunction among Parkinson's Disease Patients with Mild Cognitive Impairment pubmed:29326545 |
| Experimental gerontology | The anti-aging protein klotho alleviates injury of nigrostriatal dopaminergic pathway in 6-hydroxydopamine rat model of Parkinson's disease: Involvement of PKA/CaMKII/CREB signaling. pubmed:29107062 |
| Neurobiology of Disease | Development and biochemical characterization of a mouse model of Parkinson's disease bearing defective glucocerebrosidase activity Pubmed: 30521842 |
| molecular and cellular biochemistry | Potential therapeutic effects of antagonizing adenosine A2A receptor, curcumin and niacin in rotenone-induced Parkinson's disease mice model Pubmed: 31820278 |
| International Journal of Pharmacology | Nose to brain delivery of rotigotine loaded chitosan nanoparticles in human SH-SY5Y neuroblastoma cells and animal model of Parkinson's disease Pubmed: 32084576 |
| EBioMedicine | Anti-α-synuclein ASO delivered to monoamine neurons prevents α-synuclein accumulation in a Parkinson's disease-like mouse model and in monkeys Pubmed: 32810825 |
| Catalog No. | Related products for research use of Homo sapiens (Human) Organism species | Applications (RESEARCH USE ONLY!) |
| RPB222Hu01 | Recombinant Synuclein Alpha (SNCa) | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB222Hu01 | Polyclonal Antibody to Synuclein Alpha (SNCa) | WB; IHC; ICC; IP. |
| LAB222Hu71 | Biotin-Linked Polyclonal Antibody to Synuclein Alpha (SNCa) | WB; IHC; ICC. |
| MAB222Hu22 | Monoclonal Antibody to Synuclein Alpha (SNCa) | WB; IHC; ICC; IP. |
| SEB222Hu | ELISA Kit for Synuclein Alpha (SNCa) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| AEB222Hu | ELISA Kit for Anti-Synuclein Alpha Antibody (Anti-SNCa) | Enzyme-linked immunosorbent assay for Antibody Detection. |
