RNase Z2 Polyclonal Antibody

The protein encoded by ELAC2 (elaC ribonuclease Z 2) has a C-terminal domain with tRNA processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1  (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in ELAC2 result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for ELAC2.

The RNase Z2 Polyclonal Antibody is a highly specific and sensitive tool designed for the detection and quantification of RNase Z2 protein in various biological samples. This antibody is produced using state-of-the-art technology and has been rigorously tested to ensure its reliability and accuracy.

RNase Z2 is an essential enzyme involved in the processing of precursor tRNAs, playing a crucial role in the maturation of these molecules. Its aberrant expression or dysfunction has been implicated in various diseases, making it an important target for research and diagnostic purposes.

The RNase Z2 Polyclonal Antibody exhibits exceptional specificity, binding exclusively to the RNase Z2 protein without cross-reactivity to other related proteins. This high specificity allows for precise and reliable detection of RNase Z2 in complex biological samples.

Furthermore, this antibody demonstrates remarkable sensitivity, enabling the detection of low levels of RNase Z2 protein. This attribute is particularly advantageous when working with limited sample volumes or when studying samples with low expression levels of RNase Z2.

The RNase Z2 Polyclonal Antibody is suitable for various applications, including Western blotting, immunohistochemistry, and immunofluorescence. Its versatility allows researchers to explore the expression and localization of RNase Z2 in different tissues and cell types.

In summary, the RNase Z2 Polyclonal Antibody is a highly specific and sensitive tool that facilitates the detection and quantification of RNase Z2 protein. Its exceptional performance and versatility make it an invaluable asset for researchers and clinicians working in the field of RNA biology and related disciplines.