RPTOR Polyclonal Antibody

This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.

The RPTOR Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of RPTOR protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human RPTOR protein. The resulting polyclonal antibody exhibits high affinity and specificity towards RPTOR protein, making it an ideal tool for various applications such as Western blotting, immunohistochemistry, and immunofluorescence.

The RPTOR Polyclonal Antibody is validated for use in human, mouse, and rat samples, and has been extensively tested for its specificity and sensitivity. It is supplied as a purified IgG fraction, which has been affinity-purified using protein A chromatography. The antibody is provided in a liquid form, and is ready-to-use for various applications.

The RPTOR protein is a key component of the mTORC1 complex, which plays a critical role in regulating cell growth, proliferation, and survival. Dysregulation of mTORC1 signaling has been implicated in various diseases, including cancer, diabetes, and neurodegenerative disorders. The RPTOR Polyclonal Antibody provides a valuable tool for studying the role of RPTOR protein in these diseases, and for developing novel therapeutic strategies targeting mTORC1 signaling.

In summary, the RPTOR Polyclonal Antibody is a highly specific and sensitive immunological reagent that enables the detection and quantification of RPTOR protein in various biological samples. It is a valuable tool for studying the role of RPTOR protein in various diseases, and for developing novel therapeutic strategies targeting mTORC1 signaling.