SPAG9 Antibody / JIP-4 / JLP

C-jun-amino-terminal kinase-interacting protein 4 (JIP-4), also called JNK-associated leucine-zipper protein (JLP), is a scaffold protein that in humans is encoded by the SPAG9 gene. This gene encodes a member of the cancer testis antigen gene family. The encoded protein functions as a scaffold protein that structurally organizes mitogen-activated protein kinases and mediates c-Jun-terminal kinase signaling. This protein also binds to kinesin-1 and may be involved in microtubule-based membrane transport. This protein may play a role in tumor growth and development. Alternate splicing results in multiple transcript variants.