RT28 Polyclonal Antibody

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that has been called mitochondrial ribosomal protein S35 in the literature.

The RT28 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for use in various research applications. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to a specific region of the human RT28 protein. The resulting polyclonal antibody exhibits high affinity and specificity for the RT28 protein, making it an ideal tool for detecting and quantifying RT28 expression in various biological samples.

The RT28 Polyclonal Antibody is suitable for use in a variety of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been extensively validated for use in human tissues and cell lines, and has been shown to exhibit minimal cross-reactivity with other proteins.

This antibody is supplied as a purified IgG fraction, and is available in various sizes to meet the needs of different research applications. It is recommended for use at a dilution of 1:1000 for Western blotting, and 1:200 for immunohistochemistry and immunofluorescence.

Overall, the RT28 Polyclonal Antibody is a reliable and effective tool for studying the expression and function of the RT28 protein in various biological systems. Its high specificity and sensitivity make it an essential reagent for researchers working in the fields of cancer biology, immunology, and molecular biology.