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ELK Biotechnology
SKU(재고 관리 코드):ES10194
SCAR5 Rabbit Polyclonal Antibody
SCAR5 Rabbit Polyclonal Antibody
SCAR5 Rabbit Polyclonal Antibody
Overview
| Product name: | SCAR5 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from human protein . at AA range: 230-310 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 54kD |
| GeneID（Human）: | 286133 |
| Human Swiss-Prot No: | Q6ZMJ2 |
| Cellular localization: | Cell membrane ; Single-pass type II membrane protein . |
| Background: | function:Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1).,similarity:Belongs to the SCARA5 family.,similarity:Contains 1 collagen-like domain.,similarity:Contains 1 SRCR domain.,subunit:Homotrimer., |
| Species Reactivity: | Human;Mouse |
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