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ELK Biotechnology
SKU(재고 관리 코드):ES10277
SCNBA Rabbit Polyclonal Antibody
SCNBA Rabbit Polyclonal Antibody
SCNBA Rabbit Polyclonal Antibody
Overview
| Product name: | SCNBA rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 197kD |
| GeneID（Human）: | 11280 |
| Human Swiss-Prot No: | Q9UI33 |
| Cellular localization: | Cell membrane ; Multi-pass membrane protein . |
| Background: | Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM, Apr 2004], |
| Species Reactivity: | Human;Rat;Mouse; |
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