Sec23B Polyclonal Antibody

The Sec23 homolog B, coat complex II component encoded by SEC23B is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene.

The Sec23B Polyclonal Antibody is a highly specific and sensitive antibody that has been designed to detect the Sec23B protein in various biological samples. This antibody has been extensively validated for its specificity and sensitivity, making it an ideal tool for researchers who are interested in studying the function and regulation of the Sec23B protein.

The Sec23B protein is a member of the COPII complex, which is responsible for the transport of proteins from the endoplasmic reticulum (ER) to the Golgi apparatus. The Sec23B protein plays a critical role in this process by binding to cargo proteins and facilitating their transport through the COPII vesicles. Dysregulation of the COPII complex has been implicated in various diseases, including cancer and neurodegenerative disorders.

The Sec23B Polyclonal Antibody has been raised against a synthetic peptide corresponding to the C-terminal region of the Sec23B protein. This antibody has been purified using protein A affinity chromatography and is supplied as a liquid in phosphate-buffered saline (PBS) with 0.02% sodium azide as a preservative.

This antibody has been validated for use in various applications, including Western blotting, immunohistochemistry, and immunofluorescence. It has been shown to specifically detect the Sec23B protein in various cell lines and tissues, including human, mouse, and rat samples.

In summary, the Sec23B Polyclonal Antibody is a highly specific and sensitive tool for the detection of the Sec23B protein in various biological samples. Its validated performance and versatility make it an ideal choice for researchers studying the function and regulation of the COPII complex.