SEC62 Polyclonal Antibody

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

The SEC62 Polyclonal Antibody is a highly specific and sensitive immunological reagent designed for the detection and quantification of SEC62 protein in various biological samples. This antibody is produced by immunizing rabbits with a synthetic peptide corresponding to the C-terminal region of human SEC62 protein. The resulting polyclonal antibody exhibits high affinity and specificity towards SEC62 protein, making it an ideal tool for various applications in research and diagnostics.

The SEC62 Polyclonal Antibody has been extensively validated for its specificity and sensitivity in various assays, including Western blotting, immunohistochemistry, and immunofluorescence. It recognizes both endogenous and recombinant SEC62 protein with high specificity, and does not cross-react with other proteins or antigens. This antibody is suitable for use in a wide range of biological samples, including cell lysates, tissue extracts, and serum or plasma samples.

The SEC62 Polyclonal Antibody is supplied as a purified IgG fraction, which has been affinity-purified from rabbit serum using protein A chromatography. It is provided in a liquid form, and can be stored at -20°C for long-term use. This antibody is available in various sizes and formats, including 50 µg, 100 µg, and 500 µg sizes, as well as conjugated forms for use in various applications.

In summary, the SEC62 Polyclonal Antibody is a highly specific and sensitive immunological reagent that is ideal for the detection and quantification of SEC62 protein in various biological samples. It is a valuable tool for researchers and clinicians working in the fields of cancer biology, immunology, and diagnostics.