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ELK Biotechnology
SKU(재고 관리 코드):ES5490
SERGEF Rabbit Polyclonal Antibody
SERGEF Rabbit Polyclonal Antibody
SERGEF Rabbit Polyclonal Antibody
Overview
| Product name: | SERGEF rabbit pAb |
| Alternative Names: | SERGEF; DELGEF; GNEFR; Secretion-regulating guanine nucleotide exchange factor; Deafness locus-associated putative guanine nucleotide exchange factor; DelGEF; Guanine nucleotide exchange factor-related protein |
| Applications: | WB;ELISA;IHC |
| Recommended Dilutions: | WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000 |
| Immunogen: | The antiserum was produced against synthesized peptide derived from human SERGEF. AA range:179-228 |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 50kD |
| GeneID(Human): | 26297 |
| Human Swiss-Prot No: | Q9UGK8 |
| Cellular localization: | Cytoplasm . Nucleus . |
| Background: | function:Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 7 RCC1 repeats.,subunit:Interacts with SEC5. The interaction occurs only in the presence of magnesium or manganese and is stimulated by dCTP or GTP., |
| Species Reactivity: | Human;Rat;Mouse; |
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Western blot analysis of SERGEF Antibody. The lane on the right is blocked with the SERGEF peptide. -
Western blot analysis of the lysates from HT-29 cells using SERGEF antibody. -
Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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