Sgo2 Polyclonal Antibody

Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.

The Sgo2 Polyclonal Antibody is a highly specific and reliable tool designed for the detection and analysis of Sgo2 protein expression in various biological samples. This antibody has been meticulously developed using advanced techniques to ensure exceptional sensitivity and specificity.

The Sgo2 Polyclonal Antibody exhibits outstanding performance in a wide range of applications, including Western blotting, immunohistochemistry, and immunofluorescence. It enables researchers to accurately investigate the cellular localization and expression levels of Sgo2 protein in different tissues and cell types.

With its superior affinity and selectivity, this antibody guarantees precise and reproducible results, making it an indispensable tool for studying the role of Sgo2 in various biological processes. Its exceptional performance and reliability make it an ideal choice for both basic research and clinical applications.

The Sgo2 Polyclonal Antibody is manufactured under strict quality control standards to ensure consistent and reliable performance. It is supplied in a convenient and ready-to-use format, allowing for easy integration into laboratory workflows.

Choose the Sgo2 Polyclonal Antibody for its exceptional quality, reliability, and versatility, and unlock new insights into the function and regulation of Sgo2 protein in biological systems.