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ELK Biotechnology
SKU(재고 관리 코드):ES10242
SH2B3 Rabbit Polyclonal Antibody
SH2B3 Rabbit Polyclonal Antibody
SH2B3 Rabbit Polyclonal Antibody
Overview
| Product name: | SH2B3 rabbit pAb |
| Applications: | WB;ELISA |
| Recommended Dilutions: | WB 1:500-2000 ELISA 1:5000-20000 |
| Immunogen: | Synthesized peptide derived from part region of human protein |
| Storage: | Rabbit |
| Storage: | -20°C/1 year |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Concentration: | 1 mg/ml |
| Observed Band: | 63kD |
| GeneID（Human）: | 10019 |
| Human Swiss-Prot No: | Q9UQQ2 |
| Cellular localization: | cytosol, |
| Background: | This gene encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2014], |
| Species Reactivity: | Human;Rat;Mouse; |
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