SNAP 25 Polyclonal Antibody

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by SNAP25 (synaptosome associated protein 25) contributes the other two. Therefore, SNAP25 product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for SNAP25.

The SNAP 25 Polyclonal Antibody is a highly specific and reliable tool for the detection and analysis of SNAP 25 protein expression in various biological samples. This antibody is produced using a polyclonal approach, ensuring a high affinity and specificity towards the target protein.

The SNAP 25 Polyclonal Antibody exhibits exceptional sensitivity, allowing for the detection of even low levels of SNAP 25 protein. It has been extensively validated in various experimental settings, including Western blotting, immunohistochemistry, and immunofluorescence.

This antibody is designed to recognize both the full-length SNAP 25 protein and its isoforms, making it suitable for a wide range of applications. It has been rigorously tested to ensure minimal cross-reactivity with other proteins, ensuring accurate and reliable results.

The SNAP 25 Polyclonal Antibody is supplied as a liquid formulation, ready for immediate use. It is provided in a convenient size, allowing for multiple experiments without the need for frequent reordering.

With its exceptional specificity, sensitivity, and versatility, the SNAP 25 Polyclonal Antibody is an indispensable tool for researchers studying the role of SNAP 25 protein in various biological processes.